UniProtKB advanced search options
Last modified January 28, 2021
The advanced search interface allows to browse the different search fields and options within the dropdown menus. There is a search box right at the top when you open the blue dropdown menu that allows you to type a concept name (e.g. "structure") and receive some autocompleted suggestions from which you can then select the most suitable one:
The table below lists the different options available in the "Advanced search" menu for the UniProt Knowledgebase. Columns 2 to 4 correspond to the submenu levels that are provided for some sections, after clicking on the (sub-)section name in the advanced search interface.
The 2-letter codes in square brackets (e.g. "[DE]", "[CC]") correspond to the line codes used in the flat text files.
| UniProtKB AC | |||
| Entry name [ID] | |||
| Protein name [DE] | |||
| Gene name [GN] | |||
| Organism [OS] | |||
| Taxonomy [OC] | |||
| Virus host | |||
| Protein Existence [PE] | |||
| Evidence at protein level | |||
| Evidence at transcript level | |||
| Inferred from homology | |||
| Predicted | |||
| Uncertain | |||
| Function | |||
| Enzyme Classification [EC] | |||
| Biophysicochemical properties | |||
| Any biophysicochemical property | |||
| Absorption | |||
| Kinetic parameters | |||
| pH dependence | |||
| Redox potential | |||
| Temperature dependence | |||
| Catalytic activity | Evidence type | ||
| Activity regulation | Evidence type | ||
| Function [CC] | Evidence type | ||
| Cofactors | Cofactor | ||
| Cofactor note | |||
| Evidence type | |||
| Caution | |||
| Sites | |||
| Any site | Evidence type | ||
| Active site | Evidence type | ||
| Metal binding | Evidence type | ||
| Binding site | Evidence type | ||
| Other | Evidence type | ||
| Calcium binding | |||
| DNA binding | |||
| Nucleotide binding | |||
| Pathway | |||
| Miscellaneous [CC] | |||
| Subcellular location | |||
| Subcellular location [CC] | Evidence type | ||
| Transmembrane | Evidence type | ||
| Topological domain | Evidence type | ||
| Intramembrane | Evidence type | ||
| Pathology & Biotech | |||
| Disease | Evidence type | ||
| Allergenic properties | Evidence type | ||
| Toxic dose | |||
| Biotechnological use | |||
| Pharmaceutical use | |||
| Disruption phenotype | |||
| Mutagenesis | Evidence type | ||
| PTM / Processing | |||
| Post-translational modification [CC]] | Evidence type | ||
| Modified residue [FT] | Evidence type | ||
| Lipidation [FT] | Evidence type | ||
| Glycosylation [FT] | Evidence type | ||
| Disulfide bond [FT] | Evidence type | ||
| Cross-link [FT] | Evidence type | ||
| Molecule Processing | |||
| Any molecule processing | Evidence type | ||
| Chain | Evidence type | ||
| Initiator methionine | Evidence type | ||
| Peptide | Evidence type | ||
| Signal peptide | Evidence type | ||
| Propeptide | Evidence type | ||
| Transit peptide | Evidence type | ||
| Expression | |||
| Developmental stage | |||
| Induction | Evidence type | ||
| Tissue specificity | |||
| Interaction | |||
| Binary interaction | |||
| Subunit structure | Evidence type | ||
| Structure | |||
| 3D structure available | |||
| Secondary structure | |||
| Any secondary structure | |||
| Helix | |||
| Turn | |||
| Beta strand | |||
| Sequence | |||
| Mass (Da) | |||
| Sequence length | |||
| Alternative products | |||
| Any alternative product | Evidence type | ||
| Alternative promoter usage | Evidence type | ||
| Alternative splicing | Evidence type | ||
| Alternative initiation | Evidence type | ||
| Ribosomal frameshifting | Evidence type | ||
| Sequence caution | |||
| Any sequence caution comment | |||
| Frameshift | |||
| Erroneous initiation | |||
| Erroneous termination | |||
| Erroneous gene model prediction | |||
| Erroneous translation | |||
| Miscellaneous discrepancy | |||
| Mass spectrometry | |||
| Polymorphism | |||
| RNA Editing | Evidence type | ||
| Natural variations | |||
| Any natural variation | |||
| Natural variant | |||
| Alternative sequence | |||
| Non-standard residue | Evidence type | ||
| Non-terminal residue | |||
| Non-adjacent residues | |||
| Sequence conflict | |||
| Sequence uncertainty | |||
| Sequence features [FT] | |||
| Fragment | |||
| Sequence complete | |||
| Sequence incomplete | |||
| Encoded in | |||
| Mitochondrion | |||
| Plastid | |||
| Chloroplast | |||
| Cyanelle | |||
| Apicoplast | |||
| Organellar chromatophore | |||
| Non-photosynthetic plastid | |||
| Nucleomorph | |||
| Hydrogenosome | |||
| Precursor | |||
| Sequence requires processing | |||
| Sequence is mature | |||
| Sequence from? [RC] | |||
| Tissue | |||
| Strain | |||
| Plasmid | |||
| Transposon | |||
| Family and Domains | |||
| Domain [FT] | Evidence type | ||
| Domain comments [CC] | Evidence type | ||
| Protein family | |||
| Coiled-coil | Evidence type | ||
| Compositional bias | |||
| Motif | Evidence type | ||
| Region | Evidence type | ||
| Repeat | Evidence type | ||
| Sequence similarities | Evidence type | ||
| Zinc finger | Evidence type | ||
| Cross-references | |||
| Any cross-reference | |||
| Sequence databases | Database list | ||
| 3D structure databases | Database list | ||
| Protein-protein interaction databases | Database list | ||
| Chemistry databases | Database list | ||
| Protein family/group databases | Database list | ||
| PTM databases | Database list | ||
| Genetic variation databases | Database list | ||
| 2D gel databases | Database list | ||
| Proteomic databases | Database list | ||
| Protocols and materials databases | Database list | ||
| Genome annotation databases | Database list | ||
| Organism-specific databases | Database list | ||
| Phylogenomic databases | Database list | ||
| Enzyme and pathways databases | Database list | ||
| Family and domain databases | Database list | ||
| Gene expression databases | Database list | ||
| Other databases | Database list | ||
| Web resource | |||
| Date of | |||
| Date of creation | |||
| Date of last entry modification | |||
| Date of last sequence modification | |||
| Gene Ontology [GO] | |||
| Small molecule | |||
| Keyword [KW] | |||
| Literature Citation | |||
| Proteomes | |||
| Proteome ID | |||
| Proteome Component | |||
| Cited for | |||
| Reviewed | |||
| Reviewed | |||
| Unreviewed | |||
| Active | |||
| Active | |||
| Not active | |||
| Basket | |||
| UniRef ID | |||
| UniParc ID | |||
| Jobs (last 7 days) | |||
| Align | |||
| Blast | |||
| Retrieve/ID mapping | |||
| Job |
See also:
Simple full text search
Query fields for UniProtKB
How can I query UniProtKB annotations by evidence? - A guide to evidence codes and labels in entry view and advanced search
