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Definition

An autosomal recessive condition characterized by red blood cells that lack all Rh antigens, have increased osmotic fragility, diminished lifespan, and show changes in morphology resulting in stomatocytosis. Rh-null individuals have mild to moderate hemolytic anemia. They are at risk of having adverse reactions in response to transfusion or pregnancy, because they may produce antibodies against several of the Rh antigens.

Acronym

RHNA

Synonyms

Rh-null disease, amorph type
Rh-null syndrome, amorph type

 
Disclaimer

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