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Definition

A disorder characterized by recurrent respiratory infections, progressive airway damage, lymphopenia, increased circulating transitional B cells, increased immunoglobulin M, reduced immunoglobulin G2 levels in serum, and impaired vaccine responses.

Acronym

APDS

Synonyms

Activated PI3K-delta immunodeficiency syndrome
IMD14
Immunodeficiency 14
p110-delta-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency
PASLI

 
Disclaimer

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