Disease - Activated PI3K-delta syndrome
Definition
A disorder characterized by recurrent respiratory infections, progressive airway damage, lymphopenia, increased circulating transitional B cells, increased immunoglobulin M, reduced immunoglobulin G2 levels in serum, and impaired vaccine responses.
Acronym
APDS
Synonyms
Activated PI3K-delta immunodeficiency syndrome
IMD14
Immunodeficiency 14
p110-delta-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency
PASLI
IMD14
Immunodeficiency 14
p110-delta-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency
PASLI
Disclaimer
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
