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Definition

A slowly progressive neurodegenerative disorder characterized by bradykinesia, rigidity, resting tremor, postural instability, neuronal loss in the substantia nigra, and the presence of neurofibrillary MAPT (tau)-positive and Lewy bodies in some patients.

Acronym

PARK8

Keywords

Neurodegeneration
Parkinson disease
Parkinsonism

 
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