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Definition

Characterized by autosomal dominant inheritance of early-onset, primarily affecting skin and joint tissues. Recurring inflammatory episodes lead to accumulation of sterile, pyogenic, neutrophil-rich material within the affected joints, ultimately resulting in significant destruction.

Acronym

PAPAS

Synonyms

Familial recurrent arthritis
FRA
Pyogenic sterile arthritis, pyoderma gangrenosum and acne

 
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