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Definition

The term 'sick sinus syndrome' encompasses a variety of conditions caused by sinus node dysfunction. The most common clinical manifestations are syncope, presyncope, dizziness, and fatigue. Electrocardiogram typically shows sinus bradycardia, sinus arrest, and/or sinoatrial block. Episodes of atrial tachycardias coexisting with sinus bradycardia ('tachycardia-bradycardia syndrome') are also common in this disorder. SSS occurs most often in the elderly associated with underlying heart disease or previous cardiac surgery, but can also occur in the fetus, infant, or child without heart disease or other contributing factors. SSS1 onset is in utero, infancy, or early childhood.

Acronym

SSS1

Synonyms

Autosomal recessive sick sinus syndrome 1
Congenital absence of sinus rhythm
Familial sinus bradycardia syndrome
Familial sinus node disease autosomal recessive
Sick sinus syndrome, congenital
Sinus bradycardia syndrome, familial
Sinus node disease, familial, autosomal recessive

 
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