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Definition

A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development.

Acronym

XSCID

Synonyms

Agammaglobulinemia Swiss type
IMD4
Immunodeficiency 4
SCIDX
SCIDX1
SCID X-linked
Severe combined immunodeficiency X-linked T cell-negative/B cell-positive/NK cell-negative
Severe combined immunodeficiency X-linked T-cell negative/B-cell positive/NK-cell negative

Keywords

SCID

 
Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.

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