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Definition

An autosomal recessive disorder characterized by palmoplantar keratosis and severe periodontitis affecting deciduous and permanent dentitions and resulting in premature tooth loss. The palmoplantar keratotic phenotype vary from mild psoriasiform scaly skin to overt hyperkeratosis. Keratosis also affects other sites such as elbows and knees.

Acronym

PLS

Synonyms

Keratosis palmoplantaris with periodontopathia
PALS

Keywords

Palmoplantar keratoderma

 
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