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Definition

A disorder of apoptosis that manifests in early childhood and results in the accumulation of autoreactive lymphocytes. It is characterized by non-malignant lymphadenopathy with hepatosplenomegaly, and autoimmune hemolytic anemia, thrombocytopenia and neutropenia.

Acronym

ALPS2A

Synonyms

ALPS2
Autoimmune lymphoproliferative syndrome, type II
Autoimmune lymphoproliferative syndrome type IIA

 
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