Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

An inherited limb deformity created by insertional mutagenesis in a transgenic mouse.

Woychik R.P., Stewart T.A., Davis L.G., D'Eustachio P., Leder P.

We have created an insertional mutation that leads to a severe defect in the pattern of limb formation in the developing mouse. The novel recessive mutation is phenotypically identical and non-complementary to two previously encountered limb deformity mutations, and is closely linked to a dominant mutation that gives rise to a related limb dysmorphism. The inserted element thus provides a molecular genetic link with the control of pattern formation in the mammalian embryo.

Nature 318:36-40(1985) [PubMed] [Europe PMC]

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again