Getting started

• Text search
  Our basic text search allows you to search all the resources available

• BLAST
  Find regions of similarity between your sequences

• Sequence alignments
  Align two or more protein sequences using the Clustal Omega program

• Retrieve/ID mapping
  Batch search with UniProt IDs or convert them to another type of database ID (or vice versa)

• Peptide search
  Find sequences that exactly match a query peptide sequence

UniProt data

• Download latest release
  Get the UniProt data

• Statistics
  View Swiss-Prot and TrEMBL statistics

• How to cite us
  The UniProt Consortium

• Submit your data
  Submit your sequences, publications and annotation updates

• Programmatic access
  Query UniProt data using APIs providing REST, SPARQL and Java services

Protein spotlight

on the benefits of disorder

Like rules, paradigms are liable to be broken. By the end of the 20th century, the 'one gene - one protein' paradigm had shifted as scientists grasped the realm of mRNA splicing and post-translational modifications. Today, we know that one gene may give rise to several amino-acid sequences which can be further modified on their surface. Each of these events produces a protein with a different function…