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The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information.

New UniProt portal for the latest SARS-CoV-2 coronavirus protein entries and receptors, updated independent of the general UniProt release cycle.

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  • Forthcoming changes
    There are currently no changes planned

  • UniProt release 2021_03
    The importance of being disordered | MobiDB-lite predictions for intrinsically disordered regions | UniProtKB via AWS Open Data and Amazo...

  • UniProt release 2021_02
    With a little help from my friend | SwissBioPics subcellular location visualization | Change of evidence codes for combinatorial evidence

  • UniProt release 2021_01
    (Almost) all about that CBASS | Cross-references to VEuPathDB | Changes to humsavar.txt and related keywords | Reference proteomes downlo...

  • UniProt release 2020_06
    Venoms, gold mines for new antiprotozoal drugs | Removal of cross-references to KO


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Protein spotlight

on the benefits of disorder

Like rules, paradigms are liable to be broken. By the end of the 20th century, the 'one gene - one protein' paradigm had shifted as scientists grasped the realm of mRNA splicing and post-translational modifications. Today, we know that one gene may give rise to several amino-acid sequences which can be further modified on their surface. Each of these events produces a protein with a different function…

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