Getting started

• Text search
  Our basic text search allows you to search all the resources available

• BLAST
  Find regions of similarity between your sequences

• Sequence alignments
  Align two or more protein sequences using the Clustal Omega program

• Retrieve/ID mapping
  Batch search with UniProt IDs or convert them to another type of database ID (or vice versa)

• Peptide search
  Find sequences that exactly match a query peptide sequence

UniProt data

• Download latest release
  Get the UniProt data

• Statistics
  View Swiss-Prot and TrEMBL statistics

• How to cite us
  The UniProt Consortium

• Submit your data
  Submit your sequences, publications and annotation updates

• Programmatic access
  Query UniProt data using APIs providing REST, SPARQL and Java services

Protein spotlight

stress

Stress is a warning signal. It is like setting off a fire alarm or dialling an emergency phone number. The point is to trigger a reaction which, in the best of cases, will set things right again. We have all sensed stress at various times in our lives and, if we are attentive, our bodies react by firing off different signals: muscle stiffness, fatigue, headaches, indigestion..…