Getting started

• Text search
  Our basic text search allows you to search all the resources available

• BLAST
  Find regions of similarity between your sequences

• Sequence alignments
  Align two or more protein sequences using the Clustal Omega program

• Retrieve/ID mapping
  Batch search with UniProt IDs or convert them to another type of database ID (or vice versa)

• Peptide search
  Find sequences that exactly match a query peptide sequence

UniProt data

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  Get the UniProt data

• Statistics
  View Swiss-Prot and TrEMBL statistics

• How to cite us
  The UniProt Consortium

• Submit your data
  Submit your sequences and annotation updates

• Programmatic access
  Query UniProt data using APIs providing REST, SPARQL and Java services

Protein spotlight

best left unsaid

There are times in life when things are best left unsaid. So you bite your tongue or someone bites it for you. Either way, you are silenced and no - or less - harm is done. Nature also has its techniques for muffling genes whose products are not necessary at a given time, or that are perhaps harmful once expressed. One technique, which seems to have been with us for a very long time, is DNA methylation…