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If a protein meets these conditions... i

Common conditions

Special conditions

    • PROSITE pattern hits = PS50968
    • PROSITE pattern hits = PS50968
    • PROSITE pattern hits = PS50968

... then these annotations are applied i

Protein namei

  • Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complex (EC:

Subcellular locationi

Catalytic activityi

  • Acetyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-acetyldihydrolipoyl)lysine.

Subunit structurei

  • Forms a 24-polypeptide structural core with octahedral symmetry.

Sequence similaritiesi



  • The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.


GO (Gene Ontology) termsi

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