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If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 50 - 50 aligns to "K" in entry O31156
    • Subsequence at position 9 - 9 aligns to "D" in entry O31156
    • Subsequence at position 11 - 11 aligns to "A" in entry O31156
    • Subsequence at position 183 - 183 aligns to "D" in entry O31156
    • Subsequence at position 11 - 11 aligns to "A" in entry O31156
    • Subsequence at position 9 - 9 aligns to "D" in entry O31156
    • Subsequence at position 9 - 9 aligns to "D" in entry O31156
    • Subsequence at position 183 - 183 aligns to "D" in entry O31156
    • Subsequence at position 50 - 50 aligns to "K" in entry O31156

... then these annotations are applied i

Protein namei

  • Recommended name:
    Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
    Short name:
    Phosphonatase
    Alternative name(s):
    Phosphonoacetaldehyde phosphonohydrolase

Gene namei

  • Name:phnX

Subunit structurei

  • Homodimer.

Cofactori

  • Mg2+Note: Binds 1 Mg2+ ion per subunit.

Functioni

  • Involved in phosphonate degradation.

Sequence similaritiesi

Catalytic activityi

  • Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.

Active sitei

  • Nucleophile (to residues corresponding to position 9)
  • Schiff-base intermediate with substrate (to residues corresponding to position 50)

Metal bindingi

  • Magnesium; via carbonyl oxygen (to residues corresponding to position 11)
  • Magnesium (to residues corresponding to position 9)
  • Magnesium (to residues corresponding to position 183)

Keywordsi

GO (Gene Ontology) termsi