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If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 300 - 300 aligns to "K" in entry P42588

... then these annotations are applied i

Protein namei

  • Recommended name:
    Putrescine aminotransferase (EC:2.6.1.82)
    Alternative name(s):
    Putrescine--2-oxoglutaric acid transaminase
    Short name:
    PAT
    Short name:
    PATase

Gene namei

  • Name:patA

Pathwayi

  • Pathwayi: putrescine degradation

    This protein is involved in step 1 of the subpathway that synthesizes 4-aminobutanal from putrescine (transaminase route). This subpathway is part of the pathway putrescine degradation, which is itself part of Amine and polyamine degradation.
    View all proteins of this organism that are known to be involved in the subpathway that synthesizes 4-aminobutanal from putrescine (transaminase route), the pathway putrescine degradation and in Amine and polyamine degradation.

Sequence similaritiesi

Cofactori

Functioni

  • Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine.

Catalytic activityi

  • Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.

Modified residuei

  • N6-(pyridoxal phosphate)lysine (to residues corresponding to position 300)

Keywordsi

GO (Gene Ontology) termsi