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If a protein meets these conditions... i

Common conditions

Special conditions

    • Subsequence at position 300 - 300 aligns to "K" in entry P42588

... then these annotations are applied i

Protein namei

  • Recommended name:
    Putrescine aminotransferase (EC:2.6.1.82)
    Alternative name(s):
    Putrescine--2-oxoglutaric acid transaminase
    Short name:
    PAT
    Short name:
    PATase

Gene namei

  • Name:patA

Functioni

  • Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine.

Catalytic activityi

  • Putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.

Sequence similaritiesi

Cofactori

Pathwayi

  • Pathwayi: putrescine degradation

    This protein is involved in step 1 of the subpathway that synthesizes 4-aminobutanal from putrescine (transaminase route). This subpathway is part of the pathway putrescine degradation, which is itself part of Amine and polyamine degradation.

Modified residuei

  • N6-(pyridoxal phosphate)lysine (to residues corresponding to position 300)

Keywordsi

GO (Gene Ontology) termsi