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If a protein meets these conditions... i

Common conditions

Special conditions

    • proteome property = Membrane=2
    • proteome property = Membrane=1
    • proteome property ≠ Membrane=*
    • Subsequence at position 224 - 224 aligns to "H" in entry P0A6H8 (individually applies "")
    • Subsequence at position 226 - 226 aligns to "K" in entry P0A6H8 (individually applies "")
    • Subsequence at position 231 - 231 aligns to "D" in entry P0A6H8 (individually applies "")
    • Subsequence at position 404 - 404 aligns to "H" in entry P0A6H8 (individually applies "")
    • Subsequence at position 406 - 406 aligns to "K" in entry P0A6H8 (individually applies "")
    • Subsequence at position 411 - 411 aligns to "D" in entry P0A6H8 (individually applies "")
    • Predicted transmembrane

... then these annotations are applied i

Protein namei

  • Recommended name:
    Cardiolipin synthase A (EC:2.7.8.-)
    Short name:
    CL synthase

Gene namei

  • Name:clsA

Subcellular locationi

Functioni

  • Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.

Sequence similaritiesi

Catalytic activityi

  • 2 Phosphatidylglycerol = diphosphatidylglycerol + glycerol.

Active sitei

  • (to residues corresponding to position 224)
  • (to residues corresponding to position 226)
  • (to residues corresponding to position 231)
  • (to residues corresponding to position 404)
  • (to residues corresponding to position 406)
  • (to residues corresponding to position 411)

Transmembranei

  • Helical (to residues corresponding to positions @FROM@i - @TO@i)

Keywordsi

GO (Gene Ontology) termsi