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If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00688
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

... then these annotations are applied i

Protein namei

  • Recommended name:
    Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
    Alternative name(s):
    Phenyalanyltransferase
    Leucyltransferase
    L/F-transferase

Gene namei

  • Name:aat

Subcellular locationi

Functioni

  • Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

Catalytic activityi

  • L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].
  • L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].
  • L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].

Sequence similaritiesi

Keywordsi

GO (Gene Ontology) termsi