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If a protein meets these conditions... i

Common conditions

    • Matches HAMAP signature MF_00113
    • taxon = Bacteria
    • fragment ≠ the sequence is fragmented

... then these annotations are applied i

Protein namei

  • Recommended name:
    S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC:
    Alternative name(s):
    Queuosine biosynthesis protein QueA

Gene namei

  • Name:queA

Catalytic activityi

  • S-adenosyl-L-methionine + 7-aminomethyl-7-carbaguanosine(34) in tRNA = L-methionine + adenine + epoxyqueuosine(34) in tRNA.


  • Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

Subcellular locationi


  • Pathwayi: tRNA-queuosine biosynthesis

    This protein is involved in the pathway tRNA-queuosine biosynthesis, which is part of tRNA modification.
    View all proteins of this organism that are known to be involved in the pathway tRNA-queuosine biosynthesis and in tRNA modification.

Subunit structurei

  • Monomer.

Sequence similaritiesi


GO (Gene Ontology) termsi