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Protein
Submitted name:

Hepatic nuclear factor 4, alpha, isoform CRA_b

Gene

Hnf4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi48 – 123Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatic nuclear factor 4, alpha, isoform CRA_bImported
Submitted name:
Hepatocyte nuclear factor 4-alphaImported
Gene namesi
Name:Hnf4aImported
ORF Names:mCG_5450Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:109128 Hnf4a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000017950

Structurei

3D structure databases

SMRiZ4YKX0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 123Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4215 Eukaryota
ENOG410XQT8 LUCA
GeneTreeiENSGT00760000118948

Family and domain databases

Gene3Di3.30.50.101 hit
InterProiView protein in InterPro
IPR003068 COUP_TF
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01282 COUPTNFACTOR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

Z4YKX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMADYSAAL DPAYTTLEFE NVQVLTMGND TSPSEGANLN SSNSLGVSAL
60 70 80 90 100
CAICGDRATG KHYGASSCDG CKGFFRRSVR KNHMYSCRFS RQCVVDKDKR
110 120 130 140 150
NQCRYCRLKK CFRAGMKKEA VQNERDRIST RRSSYEDSSL PSINALLQAE
160 170 180 190 200
VLSQQITSPI SGINGDIRAK KIANITDVCE SMKEQLLVLV EWAKYIPAFC
210 220 230 240 250
ELLLDDQVAL LRAHAGEHLL LGATKRSMVF KDVLLLGNDY IVPRHCPELA
260 270 280 290 300
EMSRVSIRIL DELVLPFQEL QIDDNEYACL KAIIFFDPDA KGLSDPGKIK
310 320 330 340 350
RLRSQVQVSL EDYINDRQYD SRGRFGELLL LLPTLQSITW QMIEQIQFIK
360 370 380 390 400
LFGMAKIDNL LQEMLLGGSA SDAPHTHHPL HPHLMQEHMG TNVIVANTMP
410 420 430 440 450
SHLSNGQMCE WPRPRGQAAT PETPQPSPPS GSGSESYKLL PGAITTIVKP
460
PSAIPQPTIT KQEAI
Length:465
Mass (Da):51,725
Last modified:June 11, 2014 - v1
Checksum:i9B692DC448D385F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591488 Genomic DNA No translation available.
CH466551 Genomic DNA Translation: EDL06337.1
UniGeneiMm.202383

Genome annotation databases

EnsembliENSMUST00000109411; ENSMUSP00000105038; ENSMUSG00000017950

Similar proteinsi

Entry informationi

Entry nameiZ4YKX0_MOUSE
AccessioniPrimary (citable) accession number: Z4YKX0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: April 25, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported