Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Hepatic nuclear factor 4, alpha, isoform CRA_b

Gene

Hnf4a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi48 – 123Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Hepatic nuclear factor 4, alpha, isoform CRA_bImported
Submitted name:
Hepatocyte nuclear factor 4-alphaImported
Gene namesi
Name:Hnf4aImported
ORF Names:mCG_5450Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:109128. Hnf4a.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000017950.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 123Nuclear receptorInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG4215. Eukaryota.
ENOG410XQT8. LUCA.
GeneTreeiENSGT00760000118948.

Family and domain databases

Gene3Di1.10.565.10. 1 hit.
3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR003068. COUP_TF.
IPR035500. NHR_like_dom_sf.
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR01282. COUPTNFACTOR.
PR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Z4YKX0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDMADYSAAL DPAYTTLEFE NVQVLTMGND TSPSEGANLN SSNSLGVSAL
60 70 80 90 100
CAICGDRATG KHYGASSCDG CKGFFRRSVR KNHMYSCRFS RQCVVDKDKR
110 120 130 140 150
NQCRYCRLKK CFRAGMKKEA VQNERDRIST RRSSYEDSSL PSINALLQAE
160 170 180 190 200
VLSQQITSPI SGINGDIRAK KIANITDVCE SMKEQLLVLV EWAKYIPAFC
210 220 230 240 250
ELLLDDQVAL LRAHAGEHLL LGATKRSMVF KDVLLLGNDY IVPRHCPELA
260 270 280 290 300
EMSRVSIRIL DELVLPFQEL QIDDNEYACL KAIIFFDPDA KGLSDPGKIK
310 320 330 340 350
RLRSQVQVSL EDYINDRQYD SRGRFGELLL LLPTLQSITW QMIEQIQFIK
360 370 380 390 400
LFGMAKIDNL LQEMLLGGSA SDAPHTHHPL HPHLMQEHMG TNVIVANTMP
410 420 430 440 450
SHLSNGQMCE WPRPRGQAAT PETPQPSPPS GSGSESYKLL PGAITTIVKP
460
PSAIPQPTIT KQEAI
Length:465
Mass (Da):51,725
Last modified:June 11, 2014 - v1
Checksum:i9B692DC448D385F7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591488 Genomic DNA. No translation available.
CH466551 Genomic DNA. Translation: EDL06337.1.
UniGeneiMm.202383.

Genome annotation databases

EnsembliENSMUST00000109411; ENSMUSP00000105038; ENSMUSG00000017950.

Similar proteinsi

Entry informationi

Entry nameiZ4YKX0_MOUSE
AccessioniPrimary (citable) accession number: Z4YKX0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: November 22, 2017
This is version 36 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported