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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Mycobacterium avium MAV_120709_2344
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotationImported
ORF Names:L838_2334Imported
OrganismiMycobacterium avium MAV_120709_2344Imported
Taxonomic identifieri1335419 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium avium complex (MAC)
Proteomesi
  • UP000021340 Componenti: Unassembled WGS sequence

Subcellular locationi

X7U550:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliX7U550.
SMRiX7U550.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 93Arg_tRNA_synt_NInterPro annotationAdd BLAST90
Domaini429 – 550DALR_1InterPro annotationAdd BLAST122

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi130 – 140"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

X7U550-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPADLAELL RNTAAAVLAE RGLDAAALPA TVVVERPRNP EHGDYASNLA
60 70 80 90 100
LQLGKKVGAN PRELAGWLAA ALAETDGIAS AEVAGPGFIN LRLEASAQAV
110 120 130 140 150
VVTNVLDAGD RYGHSDAQST HNINLEFVSA NPTGPIHIGG TRWAAVGDAL
160 170 180 190 200
GRLLSTQGAG VVREYYFNDH GAQIDRFASS LIAAAKGEPT PEDGYAGSYI
210 220 230 240 250
NDIAAQVLRQ APDALSLPEP QLRETFRAIG VDLMFTHIKE SLHEFGTDFD
260 270 280 290 300
VYTHEDSMHT SGRVDQAIAR LRETGNIYEK DGATWLRTSA FGDDKDRVVI
310 320 330 340 350
KSDGKPAYIA GDIAYYLDKR QRGFDLCIYM LGADHHGYIA RLKAVAAAFG
360 370 380 390 400
DDPATVEVLI GQMVNLVRDG QPVRMSKRAG TVITLDDLVE AIGVDAARYS
410 420 430 440 450
LIRSSVDTPI DIDLALWSSA SNENPVYYVQ YAHARLSALA RNAAELGLIP
460 470 480 490 500
DTAHLELLSH DKEGTLLRTL GEFPRVLKTA ASLREPHRVC RYLEDLAGDY
510 520 530 540 550
HRFYDSCRVL PQGDEQPTDL HTARLALCQA TRQVIANGLA ILGVTAPERM
Length:550
Mass (Da):59,469
Last modified:June 11, 2014 - v1
Checksum:i91132E9C2E6EC665
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JAOP01000035 Genomic DNA. Translation: ETZ52569.1.
RefSeqiWP_003877286.1. NZ_JAOP01000035.1.

Genome annotation databases

EnsemblBacteriaiETZ52569; ETZ52569; L838_2334.
GeneIDi2718076.
PATRICifig|1335419.3.peg.2248.

Similar proteinsi

Entry informationi

Entry nameiX7U550_MYCAV
AccessioniPrimary (citable) accession number: X7U550
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: October 25, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported