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Protein

Alpha-conotoxin-like

Gene
N/A
Organism
Conus geographus (Geography cone) (Nubecula geographus)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcetylcholine receptor inhibiting toxinUniRule annotation, Neurotoxin, Postsynaptic neurotoxin, Toxin

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-conotoxin-likeUniRule annotation
OrganismiConus geographus (Geography cone) (Nubecula geographus)Imported
Taxonomic identifieri6491 [NCBI]
Taxonomic lineageiEukaryotaMetazoaLophotrochozoaMolluscaGastropodaCaenogastropodaHypsogastropodaNeogastropodaConoideaConidaeConusGastridium

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500495759622 – 63Alpha-conotoxin-likeSequence analysisAdd BLAST42

Family & Domainsi

Sequence similaritiesi

Belongs to the conotoxin A superfamily.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR009958. Conotoxin_a-typ.
IPR018072. Conotoxin_a-typ_CS.
PfamiView protein in Pfam
PF07365. Toxin_8. 1 hit.
PROSITEiView protein in PROSITE
PS60014. ALPHA_CONOTOXIN. 1 hit.

Sequencei

Sequence statusi: Complete.

X5IGW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGMRMVFTVF LLVVLAATIV SFTSDRASDG RNVAAKAFHR IGRTIRDECC
60
SNPACRVNNP HVC
Length:63
Mass (Da):6,927
Last modified:June 11, 2014 - v1
Checksum:iEF59E8A86D903B5D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB910813 mRNA. Translation: BAO65581.1.

Similar proteinsi

Entry informationi

Entry nameiX5IGW5_CONGE
AccessioniPrimary (citable) accession number: X5IGW5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: March 28, 2018
This is version 14 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)