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Protein
Submitted name:

Neuronal PAS domain protein 3 isoform G

Gene

NPAS3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal PAS domain protein 3 isoform GImported
Gene namesi
Name:NPAS3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiX5D7M0.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliX5D7M0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 74BHLHInterPro annotationAdd BLAST54
Domaini123 – 187PASInterPro annotationAdd BLAST65
Domaini304 – 359PASInterPro annotationAdd BLAST56

Phylogenomic databases

eggNOGiKOG3558. Eukaryota.
ENOG410YK57. LUCA.

Family and domain databases

CDDicd00083. HLH. 1 hit.
cd00130. PAS. 2 hits.
Gene3Di4.10.280.10. 1 hit.
InterProiView protein in InterPro
IPR011598. bHLH_dom.
IPR036638. HLH_DNA-bd_sf.
IPR000014. PAS.
IPR035965. PAS-like_dom_sf.
IPR013767. PAS_fold.
IPR013655. PAS_fold_3.
PfamiView protein in Pfam
PF00989. PAS. 1 hit.
PF08447. PAS_3. 1 hit.
SMARTiView protein in SMART
SM00353. HLH. 1 hit.
SM00091. PAS. 2 hits.
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 2 hits.
PROSITEiView protein in PROSITE
PS50888. BHLH. 1 hit.
PS50112. PAS. 2 hits.

Sequencei

Sequence statusi: Fragment.

X5D7M0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPTKPSFQQ DPSRRERLQA LRKEKSRDAA RSRRGKENFE FYELAKLLPL
60 70 80 90 100
PAAITSQLDK ASIIRLTISY LKMRDFANQG DPPWNLRMEG PPPNTSVKVI
110 120 130 140 150
GAQRRRSPSA LAIEVFEAHL GSHILQSLDG FVFALNQEGK FLYISETVSI
160 170 180 190 200
YLGLSQVELT GSSVFDYVHP GDHVEMAEQL GMKLPPGRGL LSQGTAEDGA
210 220 230 240 250
SSASSSSQSE TPEPVESTSP SLLTTDNTLE RSFFIRMKST LTKRGVHIKS
260 270 280 290 300
SGYKVIHITG RLRLRVSLSH GRTVPSQIMG LVVVAHALPP PTINEVRIDC
310 320 330 340 350
HMFVTRVNMD LNIIYCENRI SDYMDLTPVD IVGKRCYHFI HAEDVEGIRH
360 370 380 390 400
SHLDLLNKGQ CVTKYYRWMQ KNGGYIWIQS SATIAINAKN ANEKNIIWVN
410 420 430 440 450
YLLSNPEYKD TPMDIAQLPH LPEKTSESSE TSDSESDSKD TSEDNENSKS
460 470 480 490 500
DEKGNQSENS EDPEPDRKKS GNACDNDMNC NDDGHSSSNP DSRDSDDSFE
510 520 530 540 550
HSDFENPKAG EDGFGALGAM QIKVERYVES ESDLRLQNCE SLTSDSAKDS
560 570 580 590 600
DSAGEAGAQA SSKHQKRKKR RKRQKGGSAS RRRLSSASSP GGLDAGLVEP
610 620 630 640 650
PRLLSSPNSA SVLKIKTEIS EPINFDNDSS IWNYPPNREI SRNESPYSMT
660 670 680 690 700
KPPSSEHFPS PQGGGGGGGG GGGLHVAIPD SVLTPPGADG AAARKTQFGA
710 720 730 740 750
SATAALAPVA SDPLSPPLSA SPRDKHPGNG GGGGGGGGGA GGGGPSASNS
760 770 780 790 800
LLYTGDLEAL QRLQAGNVVL PLVHRVTGTL AATSTAAQRV YTTGTIRYAP
810 820 830 840 850
AEVTLAMQSN LLPNAHAVNF VDVNSPGFGL DPKTPMEMLY HHVHRLNMSG
860 870 880 890 900
PFGGAVSAAS LTQMPAGNVF TTAEGLFSTL PFPVYSNGIH AAQTLERKED
Length:900
Mass (Da):96,960
Last modified:June 11, 2014 - v1
Checksum:iE9879AC9DC90D2B5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei900Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534895 mRNA. Translation: AHW56535.1.
RefSeqiXP_011535374.1. XM_011537072.2.
UniGeneiHs.657892.
Hs.675437.
Hs.675475.

Genome annotation databases

GeneIDi64067.

Similar proteinsi

Entry informationi

Entry nameiX5D7M0_HUMAN
AccessioniPrimary (citable) accession number: X5D7M0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: November 22, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.