Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Neuronal PAS domain protein 3 isoform A

Gene

NPAS3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Neuronal PAS domain protein 3 isoform AImported
Gene namesi
Name:NPAS3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000151322.18.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiX5D2Q4.
PRIDEiX5D2Q4.

Expressioni

Gene expression databases

BgeeiENSG00000151322.
ExpressionAtlasiX5D2Q4. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliX5D2Q4.
SMRiX5D2Q4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 104BHLHInterPro annotationAdd BLAST54
Domaini153 – 217PASInterPro annotationAdd BLAST65
Domaini334 – 389PASInterPro annotationAdd BLAST56

Phylogenomic databases

eggNOGiKOG3558. Eukaryota.
ENOG410YK57. LUCA.
KOiK09098.
PhylomeDBiX5D2Q4.

Family and domain databases

CDDicd00083. HLH. 1 hit.
cd00130. PAS. 2 hits.
Gene3Di4.10.280.10. 1 hit.
InterProiView protein in InterPro
IPR011598. bHLH_dom.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR013655. PAS_fold_3.
PfamiView protein in Pfam
PF00989. PAS. 1 hit.
PF08447. PAS_3. 1 hit.
SMARTiView protein in SMART
SM00353. HLH. 1 hit.
SM00091. PAS. 2 hits.
SUPFAMiSSF47459. SSF47459. 1 hit.
SSF55785. SSF55785. 2 hits.
PROSITEiView protein in PROSITE
PS50888. BHLH. 1 hit.
PS50112. PAS. 2 hits.

Sequencei

Sequence statusi: Fragment.

X5D2Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPTKPSFQQ DPSRRERITA QHPLPNQSEC RKIYRYDGIY CESTYQNLQA
60 70 80 90 100
LRKEKSRDAA RSRRGKENFE FYELAKLLPL PAAITSQLDK ASIIRLTISY
110 120 130 140 150
LKMRDFANQG DPPWNLRMEG PPPNTSVKVI GAQRRRSPSA LAIEVFEAHL
160 170 180 190 200
GSHILQSLDG FVFALNQEGK FLYISETVSI YLGLSQVELT GSSVFDYVHP
210 220 230 240 250
GDHVEMAEQL GMKLPPGRGL LSQGTAEDGA SSASSSSQSE TPEPVESTSP
260 270 280 290 300
SLLTTDNTLE RSFFIRMKST LTKRGVHIKS SGYKVIHITG RLRLRVSLSH
310 320 330 340 350
GRTVPSQIMG LVVVAHALPP PTINEVRIDC HMFVTRVNMD LNIIYCENRI
360 370 380 390 400
SDYMDLTPVD IVGKRCYHFI HAEDVEGIRH SHLDLLNKGQ CVTKYYRWMQ
410 420 430 440 450
KNGGYIWIQS SATIAINAKN ANEKNIIWVN YLLSNPEYKD TPMDIAQLPH
460 470 480 490 500
LPEKTSESSE TSDSESDSKD TSGITEDNEN SKSDEKGNQS ENSEDPEPDR
510 520 530 540 550
KKSGNACDND MNCNDDGHSS SNPDSRDSDD SFEHSDFENP KAGEDGFGAL
560 570 580 590 600
GAMQIKVERY VESESDLRLQ NCESLTSDSA KDSDSAGEAG AQASSKHQKR
610 620 630 640 650
KKRRKRQKGG SASRRRLSSA SSPGGLDAGL VEPPRLLSSP NSASVLKIKT
660 670 680 690 700
EISEPINFDN DSSIWNYPPN REISRNESPY SMTKPPSSEH FPSPQGGGGG
710 720 730 740 750
GGGGGGLHVA IPDSVLTPPG ADGAAARKTQ FGASATAALA PVASDPLSPP
760 770 780 790 800
LSASPRDKHP GNGGGGGGGG GGAGGGGPSA SNSLLYTGDL EALQRLQAGN
810 820 830 840 850
VVLPLVHRVT GTLAATSTAA QRVYTTGTIR YAPAEVTLAM QSNLLPNAHA
860 870 880 890 900
VNFVDVNSPG FGLDPKTPME MLYHHVHRLN MSGPFGGAVS AASLTQMPAG
910 920 930
NVFTTAEGLF STLPFPVYSN GIHAAQTLER KED
Length:933
Mass (Da):100,805
Last modified:June 11, 2014 - v1
Checksum:i3215AC657CEDD9A9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei933Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KJ534894 mRNA. Translation: AHW56534.1.
RefSeqiNP_001158221.1. NM_001164749.1.
UniGeneiHs.657892.
Hs.675437.
Hs.675475.

Genome annotation databases

GeneIDi64067.
KEGGihsa:64067.
UCSCiuc001wru.4. human.

Similar proteinsi

Entry informationi

Entry nameiX5D2Q4_HUMAN
AccessioniPrimary (citable) accession number: X5D2Q4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 11, 2014
Last sequence update: June 11, 2014
Last modified: September 27, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.