mgsA

Functionⁱ

Catalytic activityⁱ

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotationSAAS annotation

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	60	UniRule annotation		1

GO - Molecular functionⁱ

methylglyoxal synthase activity Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

methylglyoxal biosynthetic process Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	LyaseUniRule annotationSAAS annotation

Molecular function

LyaseUniRule annotationSAAS annotation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Methylglyoxal synthaseUniRule annotationSAAS annotation (EC:4.2.3.3UniRule annotationSAAS annotation) Short name: MGSUniRule annotation
Gene namesⁱ	Name:mgsAUniRule annotation ORF Names:V518_0960Imported
Organismⁱ	Thermoanaerobacterium aotearoense SCUT27Imported
Taxonomic identifierⁱ	1421016 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Firmicutes › Clostridia › Thermoanaerobacterales › Thermoanaerobacterales Family III. Incertae Sedis › Thermoanaerobacterium › Thermoanaerobacterium aotearoense
Proteomesⁱ	UP000019481 Componentⁱ: Unassembled WGS sequence

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	14 – 107	MGSInterPro annotationAdd BLAST		94

Sequence similaritiesⁱ

Belongs to the methylglyoxal synthase family.UniRule annotationSAAS annotation

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01422. MGS. 1 hit.
Gene3Dⁱ	3.40.50.1380. 1 hit.
HAMAPⁱ	MF_00549. Methylglyoxal_synth. 1 hit.
InterProⁱ	View protein in InterPro IPR004363. Methylgl_synth. IPR018148. Methylglyoxal_synth_AS. IPR011607. MGS-like_dom. IPR036914. MGS-like_dom_sf.
PANTHERⁱ	PTHR30492. PTHR30492. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02142. MGS. 1 hit.
PIRSFⁱ	PIRSF006614. Methylglyox_syn. 1 hit.
SMARTⁱ	View protein in SMART SM00851. MGS. 1 hit.
SUPFAMⁱ	SSF52335. SSF52335. 1 hit.
TIGRFAMsⁱ	TIGR00160. MGSA. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01335. METHYLGLYOXAL_SYNTH. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

W9ED44-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNIALIAHDM KKSIMVDFAI AYKEILKKCN IYATGATGQL VEEATGIKVN 
        60         70         80         90        100
KFLPGPMGGD QQIGAMIAEN NMDLVIFLRD PLTAQPHEPD ILALLRVCDV 
       110        120        130 
HSIPLATNLA TAEVLIKGLD AGFLEWRDAV K

Length:131

Mass (Da):14,259

Last modified:May 14, 2014 - v1

Checksum:ⁱ2CDF131B7E82F650

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AYSN01000023 Genomic DNA. Translation: ETO38900.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_013788335.1. NZ_AYSN01000023.1.

Genome annotation databases

EnsemblBacteriaⁱ	ETO38900; ETO38900; V518_0960.
PATRICⁱ	fig\|1421016.3.peg.975.

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
W9ED44	A0A1X2FYI4 F6BHC6 I3VX73	Thermoanaerobacterium sp. PSU-2 Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11) Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485)	131	UniRef100_W9ED44	Cluster: Methylglyoxal synthase	4

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
W9ED44	Q9XCV1 D9TP33 A0A231VMF4 A0A1X2FYI4 F6BHC6 I3VX73 A0A285BIV6 L0IKG7 UPI0005EF0E39	Thermoanaerobacterium thermosaccharolyticum (Clostridium thermosaccharolyticum) Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum) Thermoanaerobacterium sp. PSU-2 Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11) Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485) Thermoanaerobacterium sp. RBIITD Thermoanaerobacterium thermosaccharolyticum M0795 Thermoanaerobacterium saccharolyticum	134	UniRef90_Q9XCV1	Cluster: Methylglyoxal synthase	10

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
W9ED44	Q9XCV1 D9TP33 A0A231VMF4 A0A285BIV6 L0IKG7 UPI0005EF0E39 A0A1X2FYI4 F6BHC6 I3VX73 UPI0006A79D69 +570	Thermoanaerobacterium thermosaccharolyticum (Clostridium thermosaccharolyticum) Thermoanaerobacterium thermosaccharolyticum (strain ATCC 7956 / DSM 571 / NCIB 9385 / NCA 3814) (Clostridium thermosaccharolyticum) Thermoanaerobacterium sp. RBIITD Thermoanaerobacterium thermosaccharolyticum M0795 Thermoanaerobacterium saccharolyticum Thermoanaerobacterium sp. PSU-2 Thermoanaerobacterium xylanolyticum (strain ATCC 49914 / DSM 7097 / LX-11) Thermoanaerobacterium saccharolyticum (strain DSM 8691 / JW/SL-YS485) Bacillus sp. FJAT-27245 Caminicella sporogenes DSM 14501 And more	134	UniRef50_Q9XCV1	Cluster: Methylglyoxal synthase	581

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AYSN01000023 Genomic DNA. Translation: ETO38900.1.
NCBI Reference Sequences More...RefSeqⁱ	WP_013788335.1. NZ_AYSN01000023.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	ETO38900; ETO38900; V518_0960.
PATRICⁱ	fig\|1421016.3.peg.975.

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01422. MGS. 1 hit.
Gene3Dⁱ	3.40.50.1380. 1 hit.
HAMAPⁱ	MF_00549. Methylglyoxal_synth. 1 hit.
InterProⁱ	View protein in InterPro IPR004363. Methylgl_synth. IPR018148. Methylglyoxal_synth_AS. IPR011607. MGS-like_dom. IPR036914. MGS-like_dom_sf.
PANTHERⁱ	PTHR30492. PTHR30492. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02142. MGS. 1 hit.
PIRSFⁱ	PIRSF006614. Methylglyox_syn. 1 hit.
SMARTⁱ	View protein in SMART SM00851. MGS. 1 hit.
SUPFAMⁱ	SSF52335. SSF52335. 1 hit.
TIGRFAMsⁱ	TIGR00160. MGSA. 1 hit.
PROSITEⁱ	View protein in PROSITE PS01335. METHYLGLYOXAL_SYNTH. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	W9ED44_9FIRM
Accessionⁱ	W9ED44Primary (citable) accession number: W9ED44
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 14, 2014
	Last sequence update:	May 14, 2014
	Last modified:	December 20, 2017
	This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - W9ED44 (W9ED44_9FIRM)

Your basket is currently empty. ⁱ

Methylglyoxal synthase

Select a section on the left to see content.

Functionⁱ

Catalytic activityⁱ

Sites

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Caution

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - W9ED44 (W9ED44_9FIRM)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Methylglyoxal synthase

mgsA

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ