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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Frankia sp. CcI6
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei394UniRule annotation1
Active sitei522UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:CcI6DRAFT_01726Imported
OrganismiFrankia sp. CcI6Imported
Taxonomic identifieri1352929 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaFrankialesFrankiaceaeFrankia
Proteomesi
  • UP000019524 Componenti: Unassembled WGS sequence

Subcellular locationi

W9D880:
  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliW9D880.
SMRiW9D880.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015. SIS_PGI_1. 1 hit.
cd05016. SIS_PGI_2. 1 hit.
Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase. 1 hit.
InterProiView protein in InterPro
IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
IPR035476. SIS_PGI_1.
IPR035482. SIS_PGI_2.
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiView protein in Pfam
PF00342. PGI. 1 hit.
PRINTSiPR00662. G6PISOMERASE.
PROSITEiView protein in PROSITE
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.

Sequencei

Sequence statusi: Complete.

W9D880-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTEPAAPV APLDITATEE WAALTTHLRE ISEVSLRDLF AADPRRGETF
60 70 80 90 100
AAEADGLYLD YSKNRLTART VELLTALARR AGLADRIEAM FRGERINVTE
110 120 130 140 150
NRPVLHVALR APAGTRIEVD GVDVVPDVHR VLDAMSQFAD RVRSGDWLGA
160 170 180 190 200
TGERIRTVVN IGIGGSDLGP AMAYDALRDY ADRSIEVRFV SNVDPTDIWE
210 220 230 240 250
ATADLDPAST LFIVSSKTFT TLETISNARA ARSWLTGLLG EDAVSRHFVA
260 270 280 290 300
VSTNAEKVAE FGIDTVNMFE FWDWVGGRYS VDCAIGLSLM IAIGPPNFRE
310 320 330 340 350
FLAGFAAMDT HFRTAPFERN LPVLLGLIGL WYRDFFGTAT HAVLPYSHYL
360 370 380 390 400
GRFPAYLQQL DMESNGKSVD LTGRPVSTPT GPIVWGTPGT NGQHAYYQLL
410 420 430 440 450
HQGTTIVPAD FIGFVRPNHP GVGTADGAGV DQHALLLANF LAQTEALAFG
460 470 480 490 500
RTAAEVAAEG VTPDLVAHRT FPGNRPSNTL LAQKLTPFAL GQLIALYEHK
510 520 530 540 550
VFTQGVIWGI NSFDQWGVEL GKVLAGRIIP ELGSEQEPEL GHDSSTNALI

KRLRAG
Length:556
Mass (Da):60,424
Last modified:May 14, 2014 - v1
Checksum:i38F6F4CD01D177A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AYTZ01000013 Genomic DNA. Translation: ETA02766.1.
RefSeqiWP_011434521.1. NZ_AYTZ01000013.1.

Genome annotation databases

EnsemblBacteriaiETA02766; ETA02766; CcI6DRAFT_01726.
GeneIDi32155082.
PATRICifig|1352929.3.peg.1803.

Similar proteinsi

Entry informationi

Entry nameiW9D880_9ACTN
AccessioniPrimary (citable) accession number: W9D880
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: September 27, 2017
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported