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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Klebsiella pneumoniae 30684/NJST258_2
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:KPNJ2_01994Imported
OrganismiKlebsiella pneumoniae 30684/NJST258_2Imported
Taxonomic identifieri1420013 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella
Proteomesi
  • UP000019586 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliW8UFU4.
SMRiW8UFU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 87Arg_tRNA_synt_NInterPro annotationAdd BLAST87
Domaini460 – 577DALR_1InterPro annotationAdd BLAST118

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi122 – 132"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

KOiK01887.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

W8UFU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIQALLSEK VSQALIAAGA PADCEPQVRQ SAKVQFGDYQ ANGVMAVAKK
60 70 80 90 100
LGMAPRQLAE QVLSHLDLNG IANKVEIAGP GFINIFLDPA FLADNVNRAL
110 120 130 140 150
QSERLGVTKP QAQTIVVDYS APNVAKEMHV GHLRSTIIGD ASVRTLEFLG
160 170 180 190 200
HKVIRANHVG DWGTQFGMLI AYLEKQQQEN AGEMALADLE GFYREAKKHY
210 220 230 240 250
DEDEAFAERA RSYVVKLQGG DEYFLQMWRK LVDITMSQNQ ITYDRLNVTL
260 270 280 290 300
TRDDVMGESL YNPMLPGIVA DLKAKGLAVE SEGATVVFLD EYKNKEGEPM
310 320 330 340 350
GVIIQKKDGG YLYTTTDIAC AKYRYETLHA DRVLYYIDSR QHQHLMQAWT
360 370 380 390 400
IVRKAGYVPD SVPLEHHMFG MMLGKDGKPF KTRAGGTVKL ADLLDEALER
410 420 430 440 450
ARRLVAEKNP DMSADELENL AKVVGIGAVK YADLSKNRTT DYVFDWDNML
460 470 480 490 500
AFEGNTAPYM QYAYTRVLSV FRKAGIDENA MIDAPVVIAE DREAQLAARL
510 520 530 540 550
LQFEETLSVV AREGTPHVMC AYLYDLAGLF SGFYEHCPIL SAESEETRNS
560 570
RLKLALLTAK TLKLGLDTLG IETVERM
Length:577
Mass (Da):64,242
Last modified:May 14, 2014 - v1
Checksum:i93D42215E0585926
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006918 Genomic DNA. Translation: AHM78774.1.
RefSeqiWP_004151452.1. NZ_CP006918.1.

Genome annotation databases

EnsemblBacteriaiAHM78774; AHM78774; KPNJ2_01994.
KEGGikps:KPNJ2_01994.
PATRICifig|1420013.3.peg.1881.

Similar proteinsi

Entry informationi

Entry nameiW8UFU4_KLEPN
AccessioniPrimary (citable) accession number: W8UFU4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: September 27, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported