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Protein

Adenylate cyclase

Gene

cyaA

Organism
Escherichia coli
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP = 3',5'-cyclic AMP + diphosphate.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionLyaseUniRule annotationImported
Biological processcAMP biosynthesisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Adenylate cyclaseUniRule annotation (EC:4.6.1.1UniRule annotation)
Gene namesi
Name:cyaAImported
ORF Names:A8C65_11025Imported, A9R57_05905Imported, AM266_12170Imported, AUQ13_19780Imported, BHS87_21320Imported, BJJ90_26125Imported, BMR42_15400Imported, BMR61_19210Imported, BUE81_11295Imported, BZL33_11395Imported, CA593_06955Imported, CIG25_19675Imported, EC3234A_71c00080Imported, ERS085365_02082Imported, ERS085416_02742Imported, ERS139211_01519Imported, ERS150873_02254Imported, PGD_00164Imported, SK85_04135Imported
OrganismiEscherichia coliImported
Taxonomic identifieri562 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000036012 Componenti: Unassembled WGS sequence
  • UP000044893 Componenti: Unassembled WGS sequence
  • UP000051850 Componenti: Unassembled WGS sequence
  • UP000216281 Componenti: Unassembled WGS sequence
  • UP000186204 Componenti: Unassembled WGS sequence
  • UP000193530 Componenti: Unassembled WGS sequence
  • UP000196822 Componenti: Unassembled WGS sequence
  • UP000070045 Componenti: Unassembled WGS sequence
  • UP000095183 Componenti: Unassembled WGS sequence
  • UP000077380 Componenti: Unassembled WGS sequence
  • UP000194199 Componenti: Chromosome
  • UP000041959 Componenti: Unassembled WGS sequence
  • UP000195107 Componenti: Unassembled WGS sequence
  • UP000042305 Componenti: Unassembled WGS sequence
  • UP000040934 Componenti: Unassembled WGS sequence
  • UP000185422 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 200Adenyl_cycl_NInterPro annotationAdd BLAST196

Sequence similaritiesi

Belongs to the adenylyl cyclase class-1 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107T0K. Bacteria.
COG3072. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR000274. Adenylate_cyclase_1.
IPR024686. Adenylate_cyclase_1_CS.
IPR024685. Adenylate_cyclase_1_N.
PANTHERiPTHR38760. PTHR38760. 1 hit.
PfamiView protein in Pfam
PF12633. Adenyl_cycl_N. 1 hit.
PF01295. Adenylate_cycl. 1 hit.
PIRSFiPIRSF001444. Adenylate_cycl. 1 hit.
PROSITEiView protein in PROSITE
PS01092. ADENYLATE_CYCLASE_1_1. 1 hit.
PS01093. ADENYLATE_CYCLASE_1_2. 1 hit.

Sequencei

Sequence statusi: Complete.

W8T0H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYLYIETLKQ RLDAINQLRV DRALAAMGPA FQQVYSLLPT LLHYHHPLMP
60 70 80 90 100
GYLDGNVPKG ICLYTPDETQ RHYLNELELY RGMSVQDPPK GELPITGVYT
110 120 130 140 150
MGSTSSVGQS CSSDLDIWVC HQSWLDSEER QLLQRKCSLL ENWAASLGVE
160 170 180 190 200
VSFFLIDENR FRHNESGSLG GEDCGSTQHI LLLDEFYRTA VRLAGKRILW
210 220 230 240 250
NMVPCDEEEH YDDYVMTLYA QGVLTPNEWL DLGGLSSLSA EEYFGASLWQ
260 270 280 290 300
LYKSIDSPYK AVLKTLLLEA YSWEYPNPRL LAKDIKQRLH DGEIVSFGLD
310 320 330 340 350
PYCMMLERVT EYLTAIEDFT RLDLVRRCFY LKVCEKLSRE RACVGWRRAV
360 370 380 390 400
LSQLVSEWGW DEARLAMLDN RANWKIDQVR EAHNELLDAM MQSYRNLIRF
410 420 430 440 450
ARRNNLSVSA SPQDIGVLTR KLYAAFEALP GKVTLVNPQI SPDLSEPNLT
460 470 480 490 500
FIYVPPGRAN RSGWYLYNRA PNIESIISHQ PLEYNRYLNK LVAWAWFNGL
510 520 530 540 550
LTSRTRLYIK GNGIVDLPKL QEMVADVSHH FPLRLPAPTP KALYSPCEIR
560 570 580 590 600
HLAIIVNLEY DPTAAFRNQV VHFDFRKLDV FSFGENQNCL VGSVDLLYRN
610 620 630 640 650
SWNEVRTLHF NGEQSMIEAL KTILGKMHQD AAPPDSVEVF CYSQHLRGLI
660 670 680 690 700
RTRVQQLVSE CIELRLSSTR QETGRFKALR VSGQTWGLFF ERLNVSVQKL
710 720 730 740 750
ENAIEFYGAI SHNKLHGLSV QVETNHVKLP AVVDGFASEG IIQFFFEETQ
760 770 780 790 800
DENGFNIYIL DESNRVEVYH HCEGSKEELV RDVSRFYSSS HDRFTYGSSF
810 820 830 840
INFNLPQFYQ IVKVDGREQV IPFRTKSIGN MPPANQDHDT PLLQQYFS
Length:848
Mass (Da):97,586
Last modified:May 14, 2014 - v1
Checksum:iF0400E3406B15018
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP017631 Genomic DNA. Translation: APT05214.1.
CP021175 Genomic DNA. Translation: ARR32864.1.
HG976957 Genomic DNA. Translation: CDU40117.1.
CYAQ01000015 Genomic DNA. Translation: CTS59827.1.
CYDH01000013 Genomic DNA. Translation: CTV63416.1.
CYCX01000020 Genomic DNA. Translation: CTW17069.1.
CYFX01000012 Genomic DNA. Translation: CTZ43021.1.
LEUM01000022 Genomic DNA. Translation: KLX92268.1.
LIVE01000017 Genomic DNA. Translation: KQJ15457.1.
LOOZ01000028 Genomic DNA. Translation: KXR88352.1.
LCVH01000071 Genomic DNA. Translation: OAC40349.1.
LZEH01000079 Genomic DNA. Translation: OEI66041.1.
MSEK01000073 Genomic DNA. Translation: OLR87310.1.
NAFT01000078 Genomic DNA. Translation: ORS98903.1.
MUAC01000019 Genomic DNA. Translation: OUK52755.1.
LYBG01000608 Genomic DNA. Translation: OWD70631.1.
NPHP01000031 Genomic DNA. Translation: OZR96428.1.
NXOA01000023 Genomic DNA. Translation: PHL39791.1.
NXOT01000048 Genomic DNA. Translation: PHL71346.1.
RefSeqiWP_000281668.1. NZ_NPHP01000031.1.

Genome annotation databases

EnsemblBacteriaiAOT35163; AOT35163; FORC31_4713.
CDU40117; CDU40117; PGD_00164.
CTS59827; CTS59827; ERS085365_02082.
CTV63416; CTV63416; ERS139211_01519.
CTW17069; CTW17069; ERS085416_02742.
CTZ43021; CTZ43021; ERS150873_02254.
KLX92268; KLX92268; SK85_04135.
KQJ15457; KQJ15457; AM266_12170.
KXQ43111; KXQ43111; AUQ01_00230.
OAC40349; OAC40349; EC3234A_71c00080.
ODH29268; ODH29268; A6803_14830.
OEI66041; OEI66041; A9R57_05905.
PATRICifig|562.10472.peg.3452.

Similar proteinsi

Entry informationi

Entry nameiW8T0H1_ECOLX
AccessioniPrimary (citable) accession number: W8T0H1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: December 20, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported