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Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Chlamydia avium 10DC88
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotationImported
ORF Names:M832_06350Imported
OrganismiChlamydia avium 10DC88Imported
Taxonomic identifieri1229831 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
Proteomesi
  • UP000019433 Componenti: Chromosome Chlamydia_sp_10DC88

Subcellular locationi

  • Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei17 – 37HelicalUniRule annotationAdd BLAST21
Transmembranei73 – 91HelicalUniRule annotationAdd BLAST19
Transmembranei97 – 114HelicalUniRule annotationAdd BLAST18
Transmembranei134 – 152HelicalUniRule annotationAdd BLAST19
Transmembranei164 – 190HelicalUniRule annotationAdd BLAST27
Transmembranei202 – 223HelicalUniRule annotationAdd BLAST22
Transmembranei229 – 250HelicalUniRule annotationAdd BLAST22
Transmembranei257 – 276HelicalUniRule annotationAdd BLAST20
Transmembranei282 – 303HelicalUniRule annotationAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

KOiK01000

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit

Sequencei

Sequence statusi: Complete.

W8JRM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYCQNVMNFM FSCFHDAPYL FLTLVFCVAL AQGWILGHPV IHWLRRQNHY
60 70 80 90 100
NQLQKAHCEK LEALHCDKAS TPTAGGILFI IVLLTAVILW LPLRNPITWL
110 120 130 140 150
SLFLIVSWGG LGWYDDIVKK RKKKGHGITV QQKFIIQFLI AAVTVVIVLY
160 170 180 190 200
TYDEPSKFYT LNVPFYGTVS LGSSFLEKFL CFILAILAIV GTSNAVNLTD
210 220 230 240 250
GLDGLASGTV SMAALSCLVI AILHITTPLA INIAVILTAL IGVCLAFLKY
260 270 280 290 300
NLPPAKVFMG DTGSLLIGGI LGSCAVMLRA ELFLILCGGV FVAEAGSVIL
310 320 330 340
QVMSWRLRKK RIFFCSPLHH HYEYQGVEEK IVVRNFWIAG FFV
Length:343
Mass (Da):38,121
Last modified:May 14, 2014 - v1
Checksum:i6D83FFA815E83F73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006571 Genomic DNA Translation: AHK63498.1

Genome annotation databases

EnsemblBacteriaiAHK63498; AHK63498; M832_06350
KEGGicav:M832_06350
PATRICifig|1229831.3.peg.644

Similar proteinsi

Entry informationi

Entry nameiW8JRM2_9CHLA
AccessioniPrimary (citable) accession number: W8JRM2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 14, 2014
Last sequence update: May 14, 2014
Last modified: September 27, 2017
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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