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Protein

RuvB-like helicase

Gene

ruvbl1

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.UniRule annotation

Catalytic activityi

ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicaseUniRule annotationSAAS annotation, Hydrolase
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, Transcription, Transcription regulationUniRule annotation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RuvB-like helicaseUniRule annotation (EC:3.6.4.12UniRule annotation)
Gene namesi
Name:ruvbl1Imported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
Proteomesi
  • UP000221080 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 365AAAInterPro annotationAdd BLAST304

Sequence similaritiesi

Belongs to the RuvB family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK04499.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR027417. P-loop_NTPase.
IPR027238. RuvB-like.
IPR037938. RUVBL1.
IPR010339. TIP49_C.
PANTHERiPTHR11093. PTHR11093. 1 hit.
PTHR11093:SF6. PTHR11093:SF6. 1 hit.
PfamiView protein in Pfam
PF06068. TIP49. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 2 hits.

Sequencei

Sequence statusi: Complete.

W5U9I3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIEEVKSTT KTQRIASHSH VKGLGLDEAG NAKQTASGLV GQETAREACG
60 70 80 90 100
IIVELIRLKK MAGRAVLLAG PPGTGKTALA LAMAQELGNK VPFCPMVGSE
110 120 130 140 150
VYSSEIKKTE VLMENFRRAI GLRIKETKEV YEGEVTELTP CETENPMGGY
160 170 180 190 200
GKTISHVIIG LKTAKGTKQL KLDPSIYESL QKERVEVGDV IYIEANSGAV
210 220 230 240 250
KRQGRCDTFA TEFDLEAEEY VPLPKGDVHK KKEIIQDVTL HDLDIANARP
260 270 280 290 300
QGGQDILSMM GQLMKAKKTE ITDKLRGEIN KVVNRYIDQG VAELVPGVLF
310 320 330 340 350
IDEVHMLDVE CFTYLHRALE SSISPIVVFA SNRGNCLIRG TEDINSPHGI
360 370 380 390 400
PLDLLDRIMI IKTVLYTPQE MKQIIKIRSQ TEGINISEEA LSHLGEIGTK
410 420 430 440 450
TTLRYAAQLL TPASLLARVQ GKEVVEREQV EEINELFYDA KSSAKILQDQ

HTKFMK
Length:456
Mass (Da):50,382
Last modified:April 16, 2014 - v1
Checksum:i73EF1A3439E41976
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JT408864 mRNA. Translation: AHH38475.1.
RefSeqiXP_017336045.1. XM_017480556.1.
UniGeneiIpu.13508.

Genome annotation databases

GeneIDi108272259.
KEGGiipu:108272259.

Similar proteinsi

Entry informationi

Entry nameiW5U9I3_ICTPU
AccessioniPrimary (citable) accession number: W5U9I3
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: March 28, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported