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Protein
Submitted name:

Lysine demethylase 4A

Gene

KDM4A

Organism
Ovis aries (Sheep)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Lysine demethylase 4AImported
Gene namesi
Name:KDM4AImported
OrganismiOvis aries (Sheep)Imported
Taxonomic identifieri9940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeCaprinaeOvis
Proteomesi
  • UP000002356 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 56JmjNInterPro annotationAdd BLAST43
Domaini142 – 312JmjCInterPro annotationAdd BLAST171
Domaini779 – 892PHD-typeInterPro annotationAdd BLAST114

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili466 – 493Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00530000063342.
OMAiCRAQGQT.
OrthoDBiEOG091G01FR.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR034732. EPHD.
IPR003347. JmjC_dom.
IPR003349. JmjN.
IPR002999. Tudor.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR013083. Znf_RING/FYVE/PHD.
PfamiView protein in Pfam
PF02373. JmjC. 1 hit.
PF02375. JmjN. 1 hit.
SMARTiView protein in SMART
SM00558. JmjC. 1 hit.
SM00545. JmjN. 1 hit.
SM00249. PHD. 2 hits.
SM00333. TUDOR. 2 hits.
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiView protein in PROSITE
PS51805. EPHD. 1 hit.
PS51184. JMJC. 1 hit.
PS51183. JMJN. 1 hit.

Sequencei

Sequence statusi: Complete.

W5NQR5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASESETLNP SARIMTFYPT MEEFRNFSRY IAYIESQGAH RAGLAKVVPP
60 70 80 90 100
KEWKPRASYD DIDDLVIPAP IQQLVTGQSG LFTQYNIQKK AMTVREFRKI
110 120 130 140 150
ANSDKYCTPR YSEFEELERK YWKNLTFNPP IYGADVNGTL YEKHVDEWNI
160 170 180 190 200
GRLRTILDLV EKESGITIEG VNTPYLYFGM WKTSFAWHTE DMDLYSINYL
210 220 230 240 250
HFGEPKSWYS VPPEHGKRLE RLAKGFFPGS AQSCEAFLRH KMTLISPLML
260 270 280 290 300
KKYGIPFDKV SGLRTQQSLA YTETPLSGYH AGFNHGFNCA ESTNFATRRW
310 320 330 340 350
IEYGKQAVLC SCRKDMVKIS MDVFVRKFQP ERYKLWKAGK DSTIIDHTLP
360 370 380 390 400
TPEAAEFLKE SELVPRAQKE EDCPEEETEG LEDGEEGDLR RSLAKHRIGT
410 420 430 440 450
KRHRVCLEIP QEVSQSELFP KEELGSGQYD MAECQAALAP VRPTHSSVRQ
460 470 480 490 500
VEDGLTFPDY SDSTEVKFEE LKNVKLEEED EDEEEEHESA ALDLSVNPAS
510 520 530 540 550
LGGRLVFSGS KKKSSSSLGS GSSQDSVSSD SETSEPLSCR AQGQTGVLTV
560 570 580 590 600
HSYAKGDGRV PSGEPCARKK GGATRSISER ELAEVADEYM FSLEESKKSK
610 620 630 640 650
GRRQPLSKLP RHHPLVLQDC VSDDELPEQL TPEEEAEETE AWAKPLSQLW
660 670 680 690 700
QNRPPNFEAE KEFNEAMAQQ APHCAVCMIF QTYHQVEFGG FGQSCGSAPD
710 720 730 740 750
LAPQIERTKP LIPEMCFTST GCTSTDINLS TPYLEEDGTS LLVSCKKCSV
760 770 780 790 800
RVHASCYGVP PAKASEDWMC SRCSANALEE DCCLCSLRGG ALQRANDDRW
810 820 830 840 850
VHVSCAVAIL EARFVNIAER SPVDVSKIPL PRFKLKCVFC KKRRKRTAGC
860 870 880 890 900
CVQCSHGRCP TAFHVSCAQA AGVMMQPDDW PFVVFITCFR HKIPNLERAK
910 920 930 940 950
GALQSITAGQ KVISKHKNGR FYQCEVVRLT TETFYEVNFD DGSFSDNLYP
960 970 980 990 1000
EDIVSQDCLQ LGPPAEGEVV QVRWTDGQVY GAKFVASHPI QMYQVEFEDG
1010 1020 1030 1040 1050
SQLVVKRDDV YTLDEELPKR VKSRLSVASD MRFNEIFTEK EVKQEKKRQR
1060 1070
VINSRYREDY IEPALYRAIM E
Length:1,071
Mass (Da):121,129
Last modified:April 16, 2014 - v1
Checksum:iC009087814DD5079
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AMGL01001121 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSOART00000000533; ENSOARP00000000505; ENSOARG00000000493.

Similar proteinsi

Entry informationi

Entry nameiW5NQR5_SHEEP
AccessioniPrimary (citable) accession number: W5NQR5
Entry historyiIntegrated into UniProtKB/TrEMBL: April 16, 2014
Last sequence update: April 16, 2014
Last modified: August 30, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported