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Protein

Enoyl-[acyl-carrier-protein] reductase [NADH]

Gene

JCM9152_4226

Organism
Bacillus hemicellulosilyticus JCM 9152
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

An acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei15NAD; via carbonyl oxygenUniRule annotation1
Binding sitei96NAD; via carbonyl oxygenUniRule annotation1
Binding sitei99Substrate; via amide nitrogen and carbonyl oxygenUniRule annotation1
Active sitei149Proton acceptorUniRule annotation1
Active sitei159Proton acceptorUniRule annotation1
Binding sitei166NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi21 – 22NADUniRule annotation2
Nucleotide bindingi68 – 69NADUniRule annotation2
Nucleotide bindingi195 – 199NADUniRule annotation5

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processFatty acid biosynthesisUniRule annotation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH]UniRule annotation (EC:1.3.1.9UniRule annotation)
Gene namesi
ORF Names:JCM9152_4226Imported
OrganismiBacillus hemicellulosilyticus JCM 9152Imported
Taxonomic identifieri1236971 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000018895 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.UniRule annotation

Family and domain databases

InterProiView protein in InterPro
IPR014358 Enoyl-ACP_Rdtase_NADH
IPR036291 NAD(P)-bd_dom_sf
IPR002347 SDR_fam
PANTHERiPTHR43159:SF2 PTHR43159:SF2, 1 hit
PIRSFiPIRSF000094 Enoyl-ACP_rdct, 1 hit
PRINTSiPR00081 GDHRDH
SUPFAMiSSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

W4QMU6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQLSLENRT YVVMGVANKR SIAWGIAQSL AKAGARLIFT YAGERLEKNV
60 70 80 90 100
RSLAETLDRS DHLILPCDVT DDAEIEKTFS QIKEEVGTIH GIAHCIAFAN
110 120 130 140 150
KDELEGEYLN TTRDGFLLAQ NISAYSLTAV VKAARPLFTE GGSILTLTYL
160 170 180 190 200
GGEKVVKNYN VMGVAKASLD ASVKYLANDL GKDNIRVNAI SAGPIRTLAA
210 220 230 240 250
KGIGGFNDVL KEIEERAPLR RTTTQEEVGD TGLFLMSDWS RGITGEIIHV

DSGYNIVSL
Length:259
Mass (Da):28,153
Last modified:March 19, 2014 - v1
Checksum:i5CC277433F0CA90E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BAUU01000045 Genomic DNA Translation: GAE32679.1
RefSeqiWP_035347110.1, NZ_BAZO01000045.1

Genome annotation databases

EnsemblBacteriaiGAE32679; GAE32679; JCM9152_4226

Similar proteinsi

Entry informationi

Entry nameiW4QMU6_9BACI
AccessioniPrimary (citable) accession number: W4QMU6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: April 25, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health