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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Streptococcus sp. BS29a
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotationSAAS annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (gpmA)
  4. Enolase (eno)
  5. Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei36SubstrateUniRule annotation1
Binding sitei121SubstrateUniRule annotation1
Binding sitei159SubstrateUniRule annotation1
Binding sitei210ATPUniRule annotation1
Binding sitei298ATP; via carbonyl oxygenUniRule annotation1
Binding sitei329ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi356 – 359ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
Biological processGlycolysisUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotationSAAS annotation (EC:2.7.2.3UniRule annotationSAAS annotation)
Gene namesi
Name:pgkUniRule annotationImported
ORF Names:HMPREF1513_1764Imported
OrganismiStreptococcus sp. BS29aImported
Taxonomic identifieri1161415 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000019043 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Monomer.UniRule annotationSAAS annotation

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni21 – 23Substrate bindingUniRule annotation3
Regioni59 – 62Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.40.50.1260, 2 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015911 Phosphoglycerate_kinase_CS
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit
PROSITEiView protein in PROSITE
PS00111 PGLYCERATE_KINASE, 1 hit

Sequencei

Sequence statusi: Complete.

W3XYV8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLTVKDVD LKGKKVLVRV DFNVPVKDGV ITNDNRITAA LPTIKYILEQ
60 70 80 90 100
GGRAILFSHL GRVKEEADKE GKSLAPVAAD LAAKLGQEVK FIPGVTRGAE
110 120 130 140 150
LEAAINALED GRQVLLVENT RFEDVDGKKE SKNDPELGKY WASLGDGIFV
160 170 180 190 200
NDAFGTAHRA HASNVGISAN VEKAVAGFLL ENEIAYIKEA VEAPERPFVA
210 220 230 240 250
ILGGSKVSDK IGVIENLLEK ADKVLIGGGM TYTFYKAQGI EIGNSLVEED
260 270 280 290 300
KLDVAKALLE KANGKLILPV DSKEANAFAD YTEVKDTEGE AVDPGFLGLD
310 320 330 340 350
IGPKSIAKFD QELTGAKTVV WNGPMGVFEN PDFQAGTIGV MDAIVKQPGV
360 370 380 390 400
KSIIGGGDSA AAAINLGRAD KFSWISTGGG ASMELLEGKV LPGLAALSEK
Length:400
Mass (Da):42,302
Last modified:March 19, 2014 - v1
Checksum:i66B35657D6376FC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZYV01000009 Genomic DNA Translation: ETS90401.1
RefSeqiWP_001096768.1, NZ_AZYV01000009.1

Genome annotation databases

EnsemblBacteriaiETS90401; ETS90401; HMPREF1513_1764
PATRICifig|1161415.3.peg.449

Similar proteinsi

Entry informationi

Entry nameiW3XYV8_9STRE
AccessioniPrimary (citable) accession number: W3XYV8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: March 28, 2018
This is version 28 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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