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Protein

Tubulin alpha chain

Gene

PFICI_01176

Organism
Pestalotiopsis fici W106-1
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin alpha chainUniRule annotation
Gene namesi
ORF Names:PFICI_01176Imported
OrganismiPestalotiopsis fici W106-1Imported
Taxonomic identifieri1229662 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesXylariomycetidaeXylarialesSporocadaceaePestalotiopsis
Proteomesi
  • UP000030651 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonSAAS annotation, MicrotubuleUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.UniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini51 – 248TubulinInterPro annotationAdd BLAST198
Domaini250 – 400Tubulin_CInterPro annotationAdd BLAST151

Sequence similaritiesi

Belongs to the tubulin family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK07374.

Family and domain databases

Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiView protein in InterPro
IPR002452. Alpha_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
PANTHERiPTHR11588. PTHR11588. 1 hit.
PfamiView protein in Pfam
PF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
PRINTSiPR01162. ALPHATUBULIN.
PR01161. TUBULIN.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEiView protein in PROSITE
PS00227. TUBULIN. 1 hit.

Sequencei

Sequence statusi: Complete.

W3XMS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGEILHLHL GQAGIQLGNS AWELYLLEHG LGADGRPVTQ EGKEQVDGGS
60 70 80 90 100
YETFFTETSG GKYVPRSIFV DLDPSPVDEI RTGDYKSLFH PELLISGKED
110 120 130 140 150
AANNYARGHY TIGKEMVDNV VDRIRRVADN CSALQGFLIF HSFGGGTGSG
160 170 180 190 200
FGALLLERLS TEYGKKCKLE FAVYPAPRVS TAVVEPYNAV LSTHSTIENS
210 220 230 240 250
DCTFLVDNEA VYDICKRNLD IPRPNYEHLN RLIAQVVSSI TSSLRFDGAL
260 270 280 290 300
NVDLNEFQTN LVPYPRIHYP LISYAPVVSA NKSSHESFKV HDLTFQCFEP
310 320 330 340 350
NNQMVVCDPR NGKYMAVALL YRGDVVPRDC NSAIAALKAK ASFNLVEWCP
360 370 380 390 400
TGFKLGINYQ KPMAVPTTSP SDGGLASVDR SVSMLSNTTA IAEAWSRLDH
410 420 430 440 450
KFDLMYSKRA FVHWYVGEGM EEGEFSEARE DLAALEKDYE EVAADSYADE

EEEAEY
Length:456
Mass (Da):50,572
Last modified:March 19, 2014 - v1
Checksum:iB0520217E4387595
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KI912109 Genomic DNA. Translation: ETS87348.1.
RefSeqiXP_007827948.1. XM_007829757.1.

Genome annotation databases

EnsemblFungiiETS87348; ETS87348; PFICI_01176.
GeneIDi19266189.
KEGGipfy:PFICI_01176.

Similar proteinsi

Entry informationi

Entry nameiW3XMS6_9PEZI
AccessioniPrimary (citable) accession number: W3XMS6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: October 25, 2017
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported