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Protein
Submitted name:

Calreticulin family protein

Gene

NECAME_09948

Organism
Necator americanus (Human hookworm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Calreticulin family proteinImported
Gene namesi
ORF Names:NECAME_09948Imported
OrganismiNecator americanus (Human hookworm)Imported
Taxonomic identifieri51031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaStrongylidaAncylostomatoideaAncylostomatidaeBunostominaeNecator
Proteomesi
  • UP000053676 Componenti: Unassembled WGS sequence

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20UniRule annotationAdd BLAST20
ChainiPRO_500515000421 – 351UniRule annotationAdd BLAST331

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the calreticulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

KOiK08057.

Family and domain databases

InterProiView protein in InterPro
IPR001580. Calret/calnex.
IPR018124. Calret/calnex_CS.
IPR009033. Calreticulin/calnexin_P_dom_sf.
IPR013320. ConA-like_dom_sf.
PANTHERiPTHR11073. PTHR11073. 1 hit.
PfamiView protein in Pfam
PF00262. Calreticulin. 1 hit.
PRINTSiPR00626. CALRETICULIN.
SUPFAMiSSF49899. SSF49899. 1 hit.
SSF63887. SSF63887. 1 hit.
PROSITEiView protein in PROSITE
PS00803. CALRETICULIN_1. 1 hit.
PS00804. CALRETICULIN_2. 1 hit.
PS00805. CALRETICULIN_REPEAT. 2 hits.

Sequencei

Sequence statusi: Complete.

W2TBF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSLVALLPV LCIAVAEVYF KEEFLDDSWK ERWVQSKHKS DYGEFVLSAG
60 70 80 90 100
KYFGDATRDQ GMKTSQDAKF YSRAAKFPKA FSNKGKTVVI QFTVKHEQGI
110 120 130 140 150
DCGGGYVKVM SSDVDLSDFH GETPYNVMFG PDICGPTKKV HVIFSYKGKN
160 170 180 190 200
HLIKKDIRCK DDELTHLYTL ILNPDNTYEV QIDGEKVESG ELESDWDLLP
210 220 230 240 250
PKKIKDPDAK KPEDWDEREY IDDADDKKPE DWDKPEHIPD PDAKKPDDWD
260 270 280 290 300
DEMDGEWEPP MIDNPEYKGE WKPKQIKNPA YKGKWIHPEI DNPEYTPDDE
310 320 330 340 350
LYLYKDWGAI GFDLWQVKSG TIFDNVLVSD SVDEAKAHAA ETFEKHFCLA

E
Length:351
Mass (Da):40,435
Last modified:March 19, 2014 - v1
Checksum:i039C264CF1CBB021
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KI659587 Genomic DNA. Translation: ETN79183.1.
RefSeqiXP_013301410.1. XM_013445956.1.

Genome annotation databases

GeneIDi25349977.
KEGGinai:NECAME_09948.

Similar proteinsi

Entry informationi

Entry nameiW2TBF3_NECAM
AccessioniPrimary (citable) accession number: W2TBF3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: November 22, 2017
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported