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Protein

Urease subunit gamma

Gene

ureA

Organism
Klebsiella pneumoniae IS22
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotationSAAS annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit alpha (ureC), Urease subunit gamma (ureA), Urease subunit alpha (ureC), Urease subunit beta (ureB), Urease subunit beta (ureB), Urease subunit gamma (ureA)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit gammaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit gammaUniRule annotation
Gene namesi
Name:ureAUniRule annotation
OrganismiKlebsiella pneumoniae IS22Imported
Taxonomic identifieri1432547 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeKlebsiella

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliW1AWD8
SMRiW1AWD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease gamma subunit family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd00390 Urease_gamma, 1 hit
Gene3Di3.30.280.10, 1 hit
HAMAPiMF_00739 Urease_gamma, 1 hit
InterProiView protein in InterPro
IPR012010 Urease_gamma
IPR002026 Urease_gamma/gamma-beta_su
IPR036463 Urease_gamma_sf
PANTHERiPTHR45301 PTHR45301, 1 hit
PfamiView protein in Pfam
PF00547 Urease_gamma, 1 hit
PIRSFiPIRSF001223 Urease_gamma, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002319 Urease_gamma_reg, 1 hit
SUPFAMiSSF54111 SSF54111, 1 hit
TIGRFAMsiTIGR00193 urease_gam, 1 hit

Sequencei

Sequence statusi: Complete.

W1AWD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELTPREKDK LLLFTAALVA ERRLARGLKL NYPESVALIS AFIMEGARDG
60 70 80 90 100
KSVASLMEEG RHVLTREQVM EGVPEMIPDI QVEATFPDGS KLVTVHNPII
Length:100
Mass (Da):11,087
Last modified:March 19, 2014 - v1
Checksum:iC5B9E7FAF615C04D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CBWF010000435 Genomic DNA Translation: CDK72696.1

Genome annotation databases

EnsemblBacteriaiCDK72696; CDK72696; CDK72696

Similar proteinsi

Entry informationi

Entry nameiW1AWD8_KLEPN
AccessioniPrimary (citable) accession number: W1AWD8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: March 28, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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