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Protein
Submitted name:

Alpha-crystallin B chain

Gene

HEL-S-101

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-crystallin B chainImported
Submitted name:
Crystallin, alpha B, isoform CRA_aImported
Submitted name:
Epididymis secretory protein Li 101Imported
Gene namesi
Name:HEL-S-101Imported
Synonyms:CRYABImported
ORF Names:hCG_1730741Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000109846.7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSG00000109846

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 164SHSPInterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3591 Eukaryota
ENOG410YERS LUCA
KOiK09542
OMAiTAPMKKL
OrthoDBiEOG091G0USC

Family and domain databases

CDDicd06498 ACD_alphaB-crystallin_HspB5, 1 hit
Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR037882 ACD_alphaB-crystallin
IPR001436 Alpha-crystallin/HSP
IPR003090 Alpha-crystallin_N
IPR031107 HSP20
IPR008978 HSP20-like_chaperone
PANTHERiPTHR11527 PTHR11527, 1 hit
PfamiView protein in Pfam
PF00525 Crystallin, 1 hit
PF00011 HSP20, 1 hit
PIRSFiPIRSF036514 Sm_HSP_B1, 1 hit
PRINTSiPR00299 ACRYSTALLIN
SUPFAMiSSF49764 SSF49764, 1 hit
PROSITEiView protein in PROSITE
PS01031 SHSP, 1 hit

Sequencei

Sequence statusi: Complete.

V9HW27-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR
60 70 80 90 100
PPSFLRAPSW FDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV
110 120 130 140 150
HGKHEERQDE HGFISREFHR KYRIPADVDP LTITSSLSSD GVLTVNGPRK
160 170
QVSGPERTIP ITREEKPAVT AAPKK
Length:175
Mass (Da):20,159
Last modified:March 19, 2014 - v1
Checksum:iAE08BED46B7849CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ224314 mRNA Translation: ACI46006.1
KM220603 mRNA Translation: AMM63597.1
KM220604 mRNA Translation: AMM63598.1
KM220605 mRNA Translation: AMM63599.1
KM220606 mRNA Translation: AMM63600.1
CH471065 Genomic DNA Translation: EAW67163.1
CH471065 Genomic DNA Translation: EAW67165.1
RefSeqiNP_001276736.1, NM_001289807.1
NP_001276737.1, NM_001289808.1
NP_001876.1, NM_001885.2
XP_011540910.1, XM_011542608.1
UniGeneiHs.53454
Hs.703770

Genome annotation databases

GeneIDi1410
KEGGihsa:1410
UCSCiuc001pmf.3 human

Similar proteinsi

Entry informationi

Entry nameiV9HW27_HUMAN
AccessioniPrimary (citable) accession number: V9HW27
Entry historyiIntegrated into UniProtKB/TrEMBL: March 19, 2014
Last sequence update: March 19, 2014
Last modified: April 25, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health