Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Complement factor H-related protein 2

Gene

CFHR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Complement factor H-related protein 2Imported
Gene namesi
Name:CFHR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000080910.11.
HGNCiHGNC:4890. CFHR2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000080910.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500477636519 – 254Sequence analysisAdd BLAST236

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi133 ↔ 176PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PeptideAtlasiV9GYE7.
PRIDEiV9GYE7.

Expressioni

Gene expression databases

BgeeiENSG00000080910.
ExpressionAtlasiV9GYE7. baseline.

Structurei

3D structure databases

ProteinModelPortaliV9GYE7.
SMRiV9GYE7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini70 – 126SushiInterPro annotationAdd BLAST57
Domaini131 – 189SushiInterPro annotationAdd BLAST59

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00900000140846.

Family and domain databases

CDDicd00033. CCP. 2 hits.
InterProiView protein in InterPro
IPR035976. Sushi/SCR/CCP_sf.
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00084. Sushi. 4 hits.
SMARTiView protein in SMART
SM00032. CCP. 4 hits.
SUPFAMiSSF57535. SSF57535. 4 hits.
PROSITEiView protein in PROSITE
PS50923. SUSHI. 2 hits.

Sequencei

Sequence statusi: Complete.

V9GYE7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWLLVSVILI SRISSVGGEA MFCDFPKINH GILYDEEKYK PFSQVPTGEV
60 70 80 90 100
FYYSCEYNFV SPSKSFWTRI TCAEEGWSPT PKCLRQTHLE GDTVQIICNT
110 120 130 140 150
GYRLQNNENN ISCVERGWST PPKCRSTISA EKCGPPPPID NGDITSFLLS
160 170 180 190 200
VYAPGSSVEY QCQNLYQLEG NNQITCRNGQ WSEPPKCLDP CVISQEIMEK
210 220 230 240 250
YNIKLKWTNQ QKLYSRTGDI VEFVCKSGYH PTKSHSFRAM CQNGKLVYPS

CEEK
Length:254
Mass (Da):28,912
Last modified:February 19, 2014 - v1
Checksum:i8CEE81841B60D079
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL139418 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000476712; ENSP00000476677; ENSG00000080910.
UCSCiuc057ocy.1. human.

Similar proteinsi

Entry informationi

Entry nameiV9GYE7_HUMAN
AccessioniPrimary (citable) accession number: V9GYE7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: October 25, 2017
This is version 26 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported