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Protein
Submitted name:

FPGT-TNNI3K readthrough

Gene

FPGT-TNNI3K

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
FPGT-TNNI3K readthroughImported
Gene namesi
Name:FPGT-TNNI3KImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000259030.6
HGNCiHGNC:42952 FPGT-TNNI3K

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000259030

PTM / Processingi

Proteomic databases

EPDiV9GXZ4
PRIDEiV9GXZ4

Expressioni

Gene expression databases

BgeeiENSG00000259030
ExpressionAtlasiV9GXZ4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliV9GXZ4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini172 – 515ANK_REP_REGIONInterPro annotationAdd BLAST344
Repeati214 – 246ANKPROSITE-ProRule annotationAdd BLAST33
Repeati247 – 279ANKPROSITE-ProRule annotationAdd BLAST33
Repeati283 – 312ANKPROSITE-ProRule annotationAdd BLAST30
Repeati313 – 345ANKPROSITE-ProRule annotationAdd BLAST33
Repeati383 – 415ANKPROSITE-ProRule annotationAdd BLAST33
Repeati453 – 485ANKPROSITE-ProRule annotationAdd BLAST33
Domaini577 – 837Protein kinaseInterPro annotationAdd BLAST261

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili135 – 162Sequence analysisAdd BLAST28

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IT5N Eukaryota
COG0666 LUCA
GeneTreeiENSGT00900000140790
OMAiPHVVNIY
OrthoDBiEOG091G01QL

Family and domain databases

CDDicd00204 ANK, 5 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
PfamiView protein in Pfam
PF12796 Ank_2, 3 hits
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 10 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 6 hits
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

V9GXZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAVRRGLRE GGAMAAARDP PEVSLREATQ RKLRRFSELR GKLVARGEFW
60 70 80 90 100
DIVAITAADE KQELAYNQQL SEKLKRKELP LGVQYHVFVD PAGAKIGNGG
110 120 130 140 150
STLCALQCLE KLYGDKWNSF TILLIHSDEW KKKVSESYVI TIERLEDDLQ
160 170 180 190 200
IKEKELTELR NIFGSDEAFS KVNLNYRTEN GLSLLHLCCI CGGKKSHIRT
210 220 230 240 250
LMLKGLRPSR LTRNGFTALH LAVYKDNAEL ITSLLHSGAD IQQVGYGGLT
260 270 280 290 300
ALHIATIAGH LEAADVLLQH GANVNIQDAV FFTPLHIAAY YGHEQVTRLL
310 320 330 340 350
LKFGADVNVS GEVGDRPLHL ASAKGFLNIA KLLMEEGSKA DVNAQDNEDH
360 370 380 390 400
VPLHFCSRFG HHDIVKYLLQ SDLEVQPHVV NIYGDTPLHL ACYNGKFEVA
410 420 430 440 450
KEIIQISGTE SLTKENIFSE TAFHSACTYG KSIDLVKFLL DQNVININHQ
460 470 480 490 500
GRDGHTGLHS ACYHGHIRLV QFLLDNGADM NLVACDPSRS SGEKDEQTCL
510 520 530 540 550
MWAYEKGHDA IVTLLKHYKR PQDELPCNEY SQPGGDGSYV SVPSPLGKIK
560 570 580 590 600
SMTKEKADIL LLRAGLPSHF HLQLSEIEFH EIIGSGSFGK VYKGRCRNKI
610 620 630 640 650
VAIKRYRANT YCSKSDVDMF CREVSILCQL NHPCVIQFVG ACLNDPSQFA
660 670 680 690 700
IVTQYISGGS LFSLLHEQKR ILDLQSKLII AVDVAKGMEY LHNLTQPIIH
710 720 730 740 750
RDLNSHNILL YEDGHAVVAD FGESRFLQSL DEDNMTKQPG NLRWMAPEVF
760 770 780 790 800
TQCTRYTIKA DVFSYALCLW EILTGEIPFA HLKPAAAAAD MAYHHIRPPI
810 820 830 840 850
GYSIPKPISS LLIRGWNACP EGRPEFSEVV MKLEECLCNI ELMSPASSNS
860 870 880 890 900
SGSLSPSSSS DCLVNRGGPG RSHVAALRSR FELEYALNAR SYAALSQSAG
910 920 930 940
QYSSQGLSLE EMKRSLQYTP IDKYGYVSDP MSSMHFHSCR NSSSFEDSS
Length:949
Mass (Da):105,589
Last modified:February 19, 2014 - v1
Checksum:i8BA9042597732BA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC093158 Genomic DNA No translation available.
AC098692 Genomic DNA No translation available.
AC105271 Genomic DNA No translation available.
AC119672 Genomic DNA No translation available.
BX470253 Genomic DNA No translation available.
RefSeqiNP_001106279.2, NM_001112808.2
UniGeneiHs.480085

Genome annotation databases

EnsembliENST00000557284; ENSP00000450895; ENSG00000259030
GeneIDi100526835
UCSCiuc001dge.4 human

Similar proteinsi

Entry informationi

Entry nameiV9GXZ4_HUMAN
AccessioniPrimary (citable) accession number: V9GXZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: March 28, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health