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Protein
Submitted name:

Uncharacterized protein

Gene

L345_12124

Organism
Ophiophagus hannah (King cobra) (Naja hannah)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi314Zinc; catalyticPROSITE-ProRule annotation1
Active sitei315PROSITE-ProRule annotation1
Metal bindingi318Zinc; catalyticPROSITE-ProRule annotation1
Metal bindingi324Zinc; catalyticPROSITE-ProRule annotation1
Active sitei862PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

LigandMetal-bindingPROSITE-ProRule annotation, ZincPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:L345_12124Imported
OrganismiOphiophagus hannah (King cobra) (Naja hannah)Imported
Taxonomic identifieri8665 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiLepidosauriaSquamataBifurcataUnidentataEpisquamataToxicoferaSerpentesColubroideaElapidaeElapinaeOphiophagus
Proteomesi
  • UP000018936 Componenti: Unassembled WGS sequence

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500477083521 – 1022Sequence analysisAdd BLAST1002

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi331 ↔ 336PROSITE-ProRule annotation
Disulfide bondi441 ↔ 461PROSITE-ProRule annotation
Disulfide bondi930 ↔ 950PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

TopDownProteomicsiV8NJI5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini186 – 375Peptidase M12BInterPro annotationAdd BLAST190
Domaini383 – 469DisintegrinInterPro annotationAdd BLAST87
Domaini725 – 942Peptidase M12BInterPro annotationAdd BLAST218
Domaini872 – 958DisintegrinInterPro annotationAdd BLAST87

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSAAS annotation

Family and domain databases

CDDicd04269. ZnMc_adamalysin_II_like. 2 hits.
Gene3Di3.40.390.10. 2 hits.
4.10.70.10. 2 hits.
InterProiView protein in InterPro
IPR006586. ADAM_Cys-rich.
IPR018358. Disintegrin_CS.
IPR001762. Disintegrin_dom.
IPR036436. Disintegrin_dom_sf.
IPR024079. MetalloPept_cat_dom_sf.
IPR001590. Peptidase_M12B.
IPR002870. Peptidase_M12B_N.
IPR034027. Reprolysin_adamalysin.
PfamiView protein in Pfam
PF08516. ADAM_CR. 2 hits.
PF00200. Disintegrin. 2 hits.
PF01562. Pep_M12B_propep. 2 hits.
PF01421. Reprolysin. 2 hits.
PRINTSiPR00289. DISINTEGRIN.
SMARTiView protein in SMART
SM00608. ACR. 2 hits.
SM00050. DISIN. 2 hits.
SUPFAMiSSF57552. SSF57552. 2 hits.
PROSITEiView protein in PROSITE
PS50215. ADAM_MEPRO. 2 hits.
PS00427. DISINTEGRIN_1. 2 hits.
PS50214. DISINTEGRIN_2. 2 hits.

Sequencei

Sequence statusi: Complete.

V8NJI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQVLLVTIC LVVFPYQGSS IILESGKVND YEVVYPQKIP VLPKSKIQRR
60 70 80 90 100
EQKMYEDTMK YEFKVNGEPV VLHLERNKEL FSKDYTETHY SPDGREITTS
110 120 130 140 150
PPVEDHCYYH GYIQSDIDST AILNACNGLK HHGEAYHIEP LKFSDSEAHA
160 170 180 190 200
VYKYENIEKE DETPKICGVK HSTWESDEPI EKISQVSITS EEFRKYSRNV
210 220 230 240 250
TAIRMRVFDM VNYITVVYKA LNIRVALIGF EIWSLKDKFV INASTKNNLL
260 270 280 290 300
HFSIWRSTVL RKRNDNAQLL TGVDLNGYTL GSAYLKAMCD VLQSVGIVQD
310 320 330 340 350
YSKSPYLVGA AMAHEIGHNL GMEHDTKTCS CMRGNCIMSP EEEGSDFPME
360 370 380 390 400
FSSCSLYDFQ NYMLTETPQC LINKPSNTSI IKNAVCGNYV EEEGEECDCG
410 420 430 440 450
SPEQCENNCC EAATCKLKPG AKCAKGACCK KCQFKKAGAE CRAARNECDL
460 470 480 490 500
PEFCIGQSAE CPMDRFHKNG HSCQNNQGYC FRGYCPTLAK QCITLWGSDA
510 520 530 540 550
KVAPDECFQN NTNGNEYDYC KKTNNVIIPC KPTKRFPVPK PNPASKMTQA
560 570 580 590 600
LLVTICLVVF PYQGRLQRHE EKTKYEDTMK YEFKLNGEPV VLNLEKNKRL
610 620 630 640 650
FSKDYTETHY SPDGREITTS PPVQDHCYYH GHIQNDADSS AVIRACDGLN
660 670 680 690 700
GYFKNNSETY IIEPLKLSDS EAHAVFKYES LEKEDETPKT CGAIHNSGES
710 720 730 740 750
DEPIEKISNI FVTPEKGEEY LEAEKYIELY IVVDNLVYRK FSCNITDVRM
760 770 780 790 800
RIFEILNYVN LYYKVFNIHV VLIGFEVWSD EDKILINGSS EPTVRSFAAW
810 820 830 840 850
RHSDLLKRKR NDNAQLLTGI RFDAGVLGIA FIGGMCNNFT SVGVIQDNSI
860 870 880 890 900
QAVLTAAVMT HELGHNLDIV PTAICGNRFV EEGEECDCGP PEICKNECCE
910 920 930 940 950
AAICKLKPEA ECASGACCDE CQFRRAGELC RAAKDDCDLD ELCTGQSAEC
960 970 980 990 1000
PMNHFHMDGY PCQNNQGYCF RGTCPTLTKQ CIALWGPDAE VAPDGCFMNN
1010 1020
QKGNDYGYCK KENGTNIPCE PE
Length:1,022
Mass (Da):115,261
Last modified:February 19, 2014 - v1
Checksum:i63F6E9CCF3D5D22B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AZIM01003442 Genomic DNA. Translation: ETE62121.1.

Entry informationi

Entry nameiV8NJI5_OPHHA
AccessioniPrimary (citable) accession number: V8NJI5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 19, 2014
Last sequence update: February 19, 2014
Last modified: January 31, 2018
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported