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Protein

Phosphoglycerate kinase

Gene

TCDM_14526

Organism
Trypanosoma cruzi Dm28c
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Glyceraldehyde-3-phosphate dehydrogenase (TCDM_02134)
  2. Phosphoglycerate kinase (TCDM_04469), Phosphoglycerate kinase (TCDM_14526), Phosphoglycerate kinase (TCDM_02085)
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. Pyruvate kinase (TCDM_00417)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
ORF Names:TCDM_14526Imported
OrganismiTrypanosoma cruzi Dm28cImported
Taxonomic identifieri1416333 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum
Proteomesi
  • UP000017861 Componenti: Unassembled WGS sequence

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Family and domain databases

CDDicd00318. Phosphoglycerate_kinase. 1 hit.
Gene3Di3.40.50.1260. 3 hits.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiView protein in InterPro
IPR001576. Phosphoglycerate_kinase.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
IPR036043. Phosphoglycerate_kinase_sf.
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiView protein in Pfam
PF00162. PGK. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 2 hits.
PROSITEiView protein in PROSITE
PS00111. PGLYCERATE_KINASE. 1 hit.

Sequencei

Sequence statusi: Complete.

V5BAG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQSTLILKKT VDDVWPLTAK RVLIRVDFNV PIHNGTITND YRIRAAIPTI
60 70 80 90 100
RRVIDQGGIC ILMSHLGRPK GVSYTSAKKD IQKRYHGGLF NDSRGKTAFF
110 120 130 140 150
AVLPGEEKAK ILALSSAKDE ASRLSLSEGS GKTAVFSRLP EEEKQTLLVR
160 170 180 190 200
YISENKEQIF PQLSLSSGYE EKLTLRPIAV RLAELLNQHV YFAHDCMDAK
210 220 230 240 250
MEISLLRRGE VXXXXLLENV RFYVEEGSKK EEERDAMARV LASYGDVYIS
260 270 280 290 300
DAFGTAHRES ATMTGIPKVL GHGAAGYLME KEISYFAKVL GSPARPLVAI
310 320 330 340 350
VGGAKVSDKI QLLDNMLQRI DHLIIGGAMA YTFLKAQGHK IGSSMCEEDK
360 370 380 390 400
LDLARSLLKK AEDRKVTVLL PVDHVCHTEF KAVETPLVTE GVDIPDGYMA
410 420 430 440 450
LDIGPRTIEK YVEIVAKCKS AIWNGPMGVF EMAPYSKGTF AIAKVMGDST
460 470 480 490 500
QNHGLMSIIG GGDSASAAEL SGEAPRMSHV STGGGASLEL LEGKTLPGVA

VLDDKE
Length:506
Mass (Da):55,257
Last modified:January 22, 2014 - v1
Checksum:iE7084374C301AC38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AYLP01000006 Genomic DNA. Translation: ESS70270.1.

Genome annotation databases

EnsemblProtistsiESS70270; ESS70270; TCDM_14526.

Similar proteinsi

Entry informationi

Entry nameiV5BAG7_TRYCR
AccessioniPrimary (citable) accession number: V5BAG7
Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: February 28, 2018
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported