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Protein

Uridine kinase

Gene

udk

Organism
Shewanella decolorationis S12
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + cytidine = ADP + CMP.UniRule annotationSAAS annotation
ATP + uridine = ADP + UMP.UniRule annotationSAAS annotation

Pathwayi: CTP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes CTP from cytidine.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. Uridine kinase (udk)
  2. no protein annotated in this organism
  3. no protein annotated in this organism
This subpathway is part of the pathway CTP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CTP from cytidine, the pathway CTP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Pathwayi: UMP biosynthesis via salvage pathway

This protein is involved in step 1 of the subpathway that synthesizes UMP from uridine.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Uridine kinase (udk)
This subpathway is part of the pathway UMP biosynthesis via salvage pathway, which is itself part of Pyrimidine metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes UMP from uridine, the pathway UMP biosynthesis via salvage pathway and in Pyrimidine metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00574; UER00637.
UPA00579; UER00640.

Names & Taxonomyi

Protein namesi
Recommended name:
Uridine kinaseUniRule annotationSAAS annotation (EC:2.7.1.48UniRule annotationSAAS annotation)
Alternative name(s):
Cytidine monophosphokinaseUniRule annotation
Uridine monophosphokinaseUniRule annotation
Gene namesi
Name:udkUniRule annotation
ORF Names:SHD_2348Imported
OrganismiShewanella decolorationis S12Imported
Taxonomic identifieri1353536 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000017548 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliV1DC57.
SMRiV1DC57.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 197PRKInterPro annotationAdd BLAST190

Sequence similaritiesi

Belongs to the uridine kinase family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd02023. UMPK. 1 hit.
HAMAPiMF_00551. Uridine_kinase. 1 hit.
InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR006083. PRK/URK.
IPR000764. Uridine_kinase-like.
IPR026008. Uridine_kinase_.
PfamiView protein in Pfam
PF00485. PRK. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00235. udk. 1 hit.

Sequencei

Sequence statusi: Complete.

V1DC57-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSQQCVIIA IAGASASGKS LIAKTIFDEL RRDLGTDQIG VINEDAYYRD
60 70 80 90 100
QSHLSMDERV LTNYDHPKAL DHQLLCTHLQ LLKSGEAVDI PCYSYTEHTR
110 120 130 140 150
MAETVKMTPK KVIILEGILL LTDPKLRELM DASVFMDTPL DICFLRRLTR
160 170 180 190 200
DVAERGRTME SVISQYKKTV RPMFLQFIEP SKQYADIIVP RGGKNRIATD
210
ILKTRIQHLL AK
Length:212
Mass (Da):24,121
Last modified:January 22, 2014 - v1
Checksum:iCEDE044FF0D737F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AXZL01000067 Genomic DNA. Translation: ESE41143.1.
RefSeqiWP_011072566.1. NZ_AXZL01000067.1.

Genome annotation databases

EnsemblBacteriaiESE41143; ESE41143; SHD_2348.
PATRICifig|1353536.3.peg.2387.

Similar proteinsi

Entry informationi

Entry nameiV1DC57_9GAMM
AccessioniPrimary (citable) accession number: V1DC57
Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: September 27, 2017
This is version 27 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported