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Protein

V-type proton ATPase subunit a

Gene

EAH_00047830

Organism
Eimeria acervulina (Coccidian parasite)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
Gene namesi
ORF Names:EAH_00047830Imported
OrganismiEimeria acervulina (Coccidian parasite)Imported
Taxonomic identifieri5801 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaConoidasidaCoccidiaEucoccidioridaEimeriorinaEimeriidaeEimeria
Proteomesi
  • UP000018050 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei588 – 621HelicalUniRule annotationAdd BLAST34
Transmembranei633 – 656HelicalUniRule annotationAdd BLAST24
Transmembranei715 – 733HelicalUniRule annotationAdd BLAST19
Transmembranei745 – 764HelicalUniRule annotationAdd BLAST20
Transmembranei931 – 952HelicalUniRule annotationAdd BLAST22

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili48 – 75Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

OMAiMFLQPEA.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiView protein in InterPro
IPR002490. V-ATPase_116kDa_su.
IPR026028. V-type_ATPase_116kDa_su_euka.
IPR015943. WD40/YVTN_repeat-like_dom_sf.
PANTHERiPTHR11629. PTHR11629. 2 hits.
PfamiView protein in Pfam
PF01496. V_ATPase_I. 2 hits.
PIRSFiPIRSF001293. ATP6V0A1. 3 hits.

Sequencei

Sequence statusi: Complete.

U6GK46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLFRSEPMR LGTLVLPQEG ARDFIVAIGT AVKVQIEDMN GMSLSRGYRR
60 70 80 90 100
QLQRLEELER ILRYLKEKIE DISGVRLVHV AQDLDRAADA AAAAAAASVY
110 120 130 140 150
NAAAAADHAD VEAAGGGAAA AASAAAAAAA AEKPQVYVLD RVEDMLNKVY
160 170 180 190 200
RQFLRFAQNN QDLQREKIAA EEELAVVSFA ASQLRSSLRS PWRLDPGSAA
210 220 230 240 250
AAAAAAAAAA AEDPKIAATS TCSSSNTLQQ QQQQQQTNTP SAATADAHAR
260 270 280 290 300
SSSARRRRPT QLSSSNSGSS SSSSWQADVQ QQEKQQTFPY SASRRLLSAG
310 320 330 340 350
GLGGLESGEM SSLVFSSVAG IVAAKDQERF ARAMFRSTRG NAFTHFKRLE
360 370 380 390 400
EEELTAYPHG EEPKSLFVTY FQGAATGSAF MEKVKCVCSA MGARTYNWPH
410 420 430 440 450
SGAEAQQRQQ QLQQLLRDKA AAAAAYEQYF LNEVGVFLEA VPASNLPLIP
460 470 480 490 500
AAASAAAAAA AAEGDLTAAA AAAAAAAAGV RRRPLITELQ RFVERERAVY
510 520 530 540 550
TTLNLFALSD ATLQADCWFL EAEEAALRKT LAQVAAEKST SAFLLVHASE
560 570 580 590 600
GLGLRSPPTS FSRCSFMSSF QGLVDTYGVA RYGEANPALF AAAIFPFLFG
610 620 630 640 650
LMFGDVGHGL LLLLLAAALL WCRSRGYVFT DELLCMLVEA RYLILLMALH
660 670 680 690 700
SIYAGFMYND VFSMGINLFG SRWGPSKEGG PPEPVAGGPY PFGVDPAWKG
710 720 730 740 750
ASNELLFLNS LKMKLAIIVG FVHMLLGLAL FILNTIHFKD WRSLLLTAVL
760 770 780 790 800
RLVLLLCLPV MFLGKPLLEL YVHRRRQPPP GFQSLNSVDS SAIQLQQLHQ
810 820 830 840 850
QQQQQQYHQP YHHHHQQQRQ QQQQYVALAT MGSRGEKDSR AAAPSAAAAA
860 870 880 890 900
VAAAGSGVAA AEEEMDVTEL WLHNMIEGIE FVLGSISNTA SYLRLWALSL
910 920 930 940 950
AHQQLSCIFF EKTVGLAFQP GLSPSQMAFK LIFFFPAFLC ITIFVMVAME
960 970 980 990
ALECFLHALR LQWVEFQNKF YKGDGVPFRP LDLNCLPGDS TS
Length:992
Mass (Da):107,528
Last modified:January 22, 2014 - v1
Checksum:i39891620956B99ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
HG671117 Genomic DNA. Translation: CDI79967.1.
RefSeqiXP_013250004.1. XM_013394550.1.

Genome annotation databases

EnsemblProtistsiCDI79967; CDI79967; EAH_00047830.
GeneIDi25272853.

Similar proteinsi

Entry informationi

Entry nameiU6GK46_EIMAC
AccessioniPrimary (citable) accession number: U6GK46
Entry historyiIntegrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: November 22, 2017
This is version 18 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported