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U5MJ28

- U5MJ28_KLEPN

UniProt

U5MJ28 - U5MJ28_KLEPN

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Protein
Xylose isomerase
Gene
xylA, D364_24050
Organism
Klebsiella pneumoniae CG43
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei101 – 1011 By similarityUniRule annotation
Active sitei104 – 1041 By similarityUniRule annotation
Metal bindingi232 – 2321Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 1 By similarityUniRule annotation
Metal bindingi268 – 2681Magnesium 2 By similarityUniRule annotation
Metal bindingi271 – 2711Magnesium 2 By similarityUniRule annotation
Metal bindingi296 – 2961Magnesium 1 By similarityUniRule annotation
Metal bindingi307 – 3071Magnesium 2 By similarityUniRule annotation
Metal bindingi309 – 3091Magnesium 2 By similarityUniRule annotation
Metal bindingi339 – 3391Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
ORF Names:D364_24050Imported
OrganismiKlebsiella pneumoniae CG43Imported
Taxonomic identifieri1244085 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
ProteomesiUP000017137: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK01805.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

U5MJ28-1 [UniParc]FASTAAdd to Basket

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MQTYFDQVDR VRFAGPITDN PLAFRHYNPD EIVLGKRMAD HLRFAACYWH    50
NFCWNGADMF GAGSFERPWQ AAGDALEMAK RKADVAFEFF YKLNVPYYCF 100
HDVDVSPEGA SLKEYLHNFA VMTEVLAEKQ QQTGVKLLWG TANCFTHPRY 150
GAGAATNPDP EVFAWAATQV VTAMNATHQL GGENYVLWGG REGYESLLNT 200
DLRQEREQIG RFLQMVVEHK HKIGFGGTLL IEPKPQEPTK HQYDYDVATV 250
YGFLKQFGLE NEIKVNIEAN HATLAGHSFH HEIASAIALG IFGSVDANRG 300
DAQLGWDTDQ FPNSVEENTL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
DMFYGHIGAM DVMALSLKLA ARMIEDGKLD QGLAKRYAGW QGELGQKIMT 400
GQMSLDNIAR YAEQHNLNPQ PQSGRQELLE NLVNTYIFG 439
Length:439
Mass (Da):49,380
Last modified:January 22, 2014 - v1
Checksum:iD63250644958A8D9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP006648 Genomic DNA. Translation: AGX40605.1.
RefSeqiYP_008663232.1. NC_022566.1.

Genome annotation databases

EnsemblBacteriaiAGX40605; AGX40605; D364_24050.
GeneIDi17170298.
KEGGikpi:D364_24050.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP006648 Genomic DNA. Translation: AGX40605.1 .
RefSeqi YP_008663232.1. NC_022566.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AGX40605 ; AGX40605 ; D364_24050 .
GeneIDi 17170298.
KEGGi kpi:D364_24050.

Phylogenomic databases

KOi K01805.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of Klebsiella pneumoniae CG43, a K2 serotype liver abscess isolate."
    Lin F.Y., Lo Y.L., Tang C.Y., Chen Y.T., Lu C.W., Wang W.C., Peng H.L., Chang H.Y.
    Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CG43Imported.

Entry informationi

Entry nameiU5MJ28_KLEPN
AccessioniPrimary (citable) accession number: U5MJ28
Entry historyi
Integrated into UniProtKB/TrEMBL: January 22, 2014
Last sequence update: January 22, 2014
Last modified: June 11, 2014
This is version 6 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi