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Protein
Submitted name:

Proprotein convertase subtilisin/kexin type 1

Gene

PCSK1

Organism
Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Protein family/group databases

MEROPSiS08.072

Names & Taxonomyi

Protein namesi
Submitted name:
Proprotein convertase subtilisin/kexin type 1Imported
Gene namesi
Name:PCSK1Imported
OrganismiFicedula albicollis (Collared flycatcher) (Muscicapa albicollis)Imported
Taxonomic identifieri59894 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaePasseriformesMuscicapidaeFicedula
Proteomesi
  • UP000016665 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500464464429 – 749Sequence analysisAdd BLAST721

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini461 – 598P/Homo BInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00750000117358
KOiK01359
OMAiFEPRALK
OrthoDBiEOG091G05HI

Family and domain databases

CDDicd04059 Peptidases_S8_Protein_converta, 1 hit
Gene3Di2.60.120.260, 1 hit
3.30.70.850, 1 hit
3.40.50.200, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR034182 Kexin/furin
IPR002884 P_dom
IPR000209 Peptidase_S8/S53_dom
IPR036852 Peptidase_S8/S53_dom_sf
IPR023827 Peptidase_S8_Asp-AS
IPR022398 Peptidase_S8_His-AS
IPR023828 Peptidase_S8_Ser-AS
IPR015500 Peptidase_S8_subtilisin-rel
IPR022005 Proho_convert
IPR032815 S8_pro-domain
IPR038466 S8_pro-domain_sf
PfamiView protein in Pfam
PF01483 P_proprotein, 1 hit
PF00082 Peptidase_S8, 1 hit
PF12177 Proho_convert, 1 hit
PF16470 S8_pro-domain, 1 hit
PRINTSiPR00723 SUBTILISIN
SUPFAMiSSF49785 SSF49785, 1 hit
SSF52743 SSF52743, 1 hit
PROSITEiView protein in PROSITE
PS51829 P_HOMO_B, 1 hit
PS00136 SUBTILASE_ASP, 1 hit
PS00137 SUBTILASE_HIS, 1 hit
PS00138 SUBTILASE_SER, 1 hit

Sequencei

Sequence statusi: Complete.

U3JJX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGRRWAGRC AALAVLLAAW SLPQGGSAGR LFLNEWAAEI PAGPDAARAI
60 70 80 90 100
ADELDYDLVG QIGSLKNHYL FRHKSHPRRS RRSATHMTKR LSDDERVSWA
110 120 130 140 150
EQQYEKKRTK RASVRDSAES LFNDPMWNQQ WYLQDTRITP SLPKLDLHVI
160 170 180 190 200
PVWQKGFTGK GVVITVLDDG LEWNHTDIYA NYDPKASYDF NDNDHDPFPR
210 220 230 240 250
YDPTNENKHG TRCAGEIAMQ ANNRKCGVGV AYNSRVGGIR MLDGIVTDAI
260 270 280 290 300
EASSIGFNPE HVDIYSASWG PNDDGKTVEG PGRLAQKAFE YGINQGRNGK
310 320 330 340 350
GSIFVWASGN GGRQGDNCDC DGYTDSIYTI SISSASQQGL SPWYAEKCSS
360 370 380 390 400
TLATAYSSGD YTDQRITSVD LHNECTETHT GTSASAPLAA GIFALALEAN
410 420 430 440 450
PDLTWRDMQH LVVWTSEYDP LAGNPGWKKN GAGLMVNSRF GFGLLNANAL
460 470 480 490 500
VDLADPKRWK GVPEKRECIV KDKSFEPRLL RADEEVIIEI PTKACEGQEN
510 520 530 540 550
SIASLEHVQL EATIEYSRRG DLHVTLVSPS GTSTVLLAER ERDKSPNGFK
560 570 580 590 600
NWDFMSVHTW GENPAGTWIL RITDMSRRIQ NEGRIVNWKL ILHGTTTQPE
610 620 630 640 650
HMKQPRVYTS YNAVQNDRRG VEKMTDLVED HTTLESLSEK PKATEETSSS
660 670 680 690 700
SDKAEDKIPS EAMLHLLQSA FSRQMDQKQL PKKTASKKLN IPYEHFYQAL
710 720 730 740
KKLNKPSQLR GSEESLYSDY VDLFYNAKPY KHRDDRLLQA LVDIINEGN
Length:749
Mass (Da):83,839
Last modified:November 13, 2013 - v1
Checksum:i79C42B2B7597B741
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AGTO01001632 Genomic DNA No translation available.
RefSeqiXP_005061274.1, XM_005061217.1

Genome annotation databases

EnsembliENSFALT00000003090; ENSFALP00000003077; ENSFALG00000002956
GeneIDi101816616
KEGGifab:101816616

Similar proteinsi

Entry informationi

Entry nameiU3JJX3_FICAL
AccessioniPrimary (citable) accession number: U3JJX3
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: May 23, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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