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Protein
Submitted name:

E3 ubiquitin-protein ligase BRE1B isoform 1

Gene

RNF40

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseImported
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase BRE1B isoform 1Imported
Gene namesi
Name:RNF40Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini948 – 987RING-typeInterPro annotationAdd BLAST40

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili63 – 83Sequence analysisAdd BLAST21
Coiled coili230 – 306Sequence analysisAdd BLAST77
Coiled coili329 – 373Sequence analysisAdd BLAST45
Coiled coili438 – 465Sequence analysisAdd BLAST28
Coiled coili487 – 521Sequence analysisAdd BLAST35
Coiled coili627 – 672Sequence analysisAdd BLAST46
Coiled coili686 – 720Sequence analysisAdd BLAST35
Coiled coili723 – 757Sequence analysisAdd BLAST35
Coiled coili765 – 785Sequence analysisAdd BLAST21
Coiled coili800 – 820Sequence analysisAdd BLAST21
Coiled coili828 – 848Sequence analysisAdd BLAST21
Coiled coili898 – 925Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0978 Eukaryota
ENOG410Y5C6 LUCA
KOiK10696

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR013956 E3_ubiquit_lig_Bre1
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR23163 PTHR23163, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
PROSITEiView protein in PROSITE
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

U3DM56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGPGNKRAA GDGGSGPPEK KLSREEKTTT TLIEPIRLGG ISSTEEMDLK
60 70 80 90 100
VLQFKNKKLA ERLEQRQACE DELRERIEKL EKRQATDDAT LFIVNRYWAQ
110 120 130 140 150
LDETVEALLR CHESQGELSS VPEAPGTQEG LTCDGTPLPE PGTSELREPL
160 170 180 190 200
PMQLRPPLSE PALAFVVALG ASSSEEVELE LQGRMEFSKA AVSRVVEASD
210 220 230 240 250
RLQRRVEELC QRVYSRGDSE PLSEAARART RELGRENRRL QDLATQLQEK
260 270 280 290 300
HHRISLEYSE LQDKVTSAET KVLEMETTVE DLQWDIEKLR KREQKLNKHL
310 320 330 340 350
AEALEQLNSG YYVSGSSSGF QGGQITLSMQ KFEMLNAELE ENQELANSRM
360 370 380 390 400
AELEKLQAEL QGAVRTNERL KVALRSLPEE VVRETTEYRV LQSQFSLLYN
410 420 430 440 450
ESLQVKTQLD EARGLLLATK NSHLRHIEHM ESDELGLQKK LRTEVIQLED
460 470 480 490 500
TLAQVRKEYE MLRIEFEQNL AANEQAGPIN REMRHLISSL QNHNHQLKGD
510 520 530 540 550
AQRYKRKLRE VQAEIGKLRA QPSGSTHSTP NVGHSEDSGL NAPAPGKEEG
560 570 580 590 600
GPGPVSIPDN RKEMAPMPGT TTTASSVKKE ELVPSEEDVQ ALTPGAQGPS
610 620 630 640 650
FRGREPEARP KRELREREGP SLGPLPVASA LSRAEREKAK VEEAKRKESE
660 670 680 690 700
LLKGLRAELK KAQESQKEMK LLLDMYKSAP KEQRDKVQLM AAERKAKAEV
710 720 730 740 750
DELRSRIREL EERDRRESKK IADEDALRRI RQAEEQIEHL QRKLGATKQE
760 770 780 790 800
EEALLSEMDV TGQAFEDMQE QNGRLLQQLR EKDDANFKLM SERIKANQIH
810 820 830 840 850
KLLREEKDEL GEQVLGLKSQ VDAQLLTVQK LEEKERALQG SLGGVEKELT
860 870 880 890 900
LRSQALELNK RKAVEAAQLA EDLKVQLEHV QTRLREIQPC LAESRAAREK
910 920 930 940 950
ESFNLKRAQE DISRLRRKLE KQRKVEVYAD ADEILQEEIK EYKARLTCPC
960 970 980 990 1000
CNTRKKDAVL TKCFHVFCFE CVRGRYEARQ RKCPKCNAAF GAHDFHRIYI

S
Length:1,001
Mass (Da):113,929
Last modified:November 13, 2013 - v1
Checksum:i609D93E76B148884
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01001016 mRNA Translation: JAB10845.1
GAMR01000728 mRNA Translation: JAB33204.1
GAMQ01001709 mRNA Translation: JAB40142.1
GAMP01006522 mRNA Translation: JAB46233.1
RefSeqiXP_017834356.1, XM_017978867.1

Genome annotation databases

GeneIDi100413479
KEGGicjc:100413479

Similar proteinsi

Entry informationi

Entry nameiU3DM56_CALJA
AccessioniPrimary (citable) accession number: U3DM56
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: April 25, 2018
This is version 23 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health