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Protein
Submitted name:

Interstitial collagenase isoform 1 preproprotein

Gene

MMP1

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Cofactori

Zn2+SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei221UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, MetalloproteaseSAAS annotation, Protease
LigandCalciumSAAS annotation, Metal-bindingSAAS annotation, ZincSAAS annotation

Protein family/group databases

MEROPSiM10.001.

Names & Taxonomyi

Protein namesi
Submitted name:
Interstitial collagenase isoform 1 preproproteinImported
Gene namesi
Name:MMP1Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500464111922 – 471Sequence analysisAdd BLAST450

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini107 – 264ZnMcInterPro annotationAdd BLAST158
Repeati277 – 326HemopexinPROSITE-ProRule annotationAdd BLAST50
Repeati327 – 373HemopexinPROSITE-ProRule annotationAdd BLAST47
Repeati376 – 424HemopexinPROSITE-ProRule annotationAdd BLAST49
Repeati425 – 468HemopexinPROSITE-ProRule annotationAdd BLAST44

Sequence similaritiesi

Belongs to the peptidase M10A family.SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1565. Eukaryota.
ENOG410XQ5D. LUCA.

Family and domain databases

CDDicd00094. HX. 1 hit.
cd04278. ZnMc_MMP. 1 hit.
Gene3Di2.110.10.10. 1 hit.
3.40.390.10. 1 hit.
InterProiView protein in InterPro
IPR000585. Hemopexin-like_dom.
IPR036375. Hemopexin-like_dom_sf.
IPR018487. Hemopexin-like_repeat.
IPR018486. Hemopexin_CS.
IPR033739. M10A_MMP.
IPR024079. MetalloPept_cat_dom.
IPR001818. Pept_M10_metallopeptidase.
IPR021190. Pept_M10A.
IPR021158. Pept_M10A_Zn_BS.
IPR006026. Peptidase_Metallo.
IPR002477. Peptidoglycan-bd-like.
IPR036365. PGBD-like_sf.
PfamiView protein in Pfam
PF00045. Hemopexin. 4 hits.
PF00413. Peptidase_M10. 1 hit.
PF01471. PG_binding_1. 1 hit.
PIRSFiPIRSF001191. Peptidase_M10A_matrix. 1 hit.
PRINTSiPR00138. MATRIXIN.
SMARTiView protein in SMART
SM00120. HX. 4 hits.
SM00235. ZnMc. 1 hit.
SUPFAMiSSF47090. SSF47090. 1 hit.
SSF50923. SSF50923. 1 hit.
PROSITEiView protein in PROSITE
PS00546. CYSTEINE_SWITCH. 1 hit.
PS00024. HEMOPEXIN. 1 hit.
PS51642. HEMOPEXIN_2. 4 hits.

Sequencei

Sequence statusi: Complete.

U3CMY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSCPPPLLL LLLFWAVVSH GFPATLETQE PDVEIVQKYL ERYYNLRNDG
60 70 80 90 100
KLVEKQRNSG PVVEKLKQMQ EFFGLKVTGK PDAETLHVMK QPRCGVPDVA
110 120 130 140 150
RFVLTEGNPR WEKTHLTYRI ENYTPDLPRA DVDHAIEKAF QLWSNVTPLT
160 170 180 190 200
FTKVPKGQAD IMISFVRGDH RDNSPFDGPG GNLAHAFQPG PGIGGDAHFD
210 220 230 240 250
EDEMWTNNFR EYNLYRVAAH ELGHSLGLSH STDIGALMFP SYTFSGDVQL
260 270 280 290 300
AQDDINGIQA IYGRSQNPVQ PTGPQTPQVC DSKLTFDAVT TLRGEVMFFK
310 320 330 340 350
DRFYMRTNPF YPEVELNFIS VFWPQLPNGL EAAYEFADRD EVRFFKGNKY
360 370 380 390 400
WAVQGQNVLH GYPKDIYSSF GFPRTVKHID AALSEENTGK TYFFVGNKYW
410 420 430 440 450
RYDEYKRSMD AGYPKMIAHD FPGIGHKVDA VFMKDGFFYF FHGTRQYKFD
460 470
PKTKRILTLQ KANSWFNCRK N
Length:471
Mass (Da):54,077
Last modified:November 13, 2013 - v1
Checksum:iD1676E6D32D7A05C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01009240 mRNA. Translation: JAB02621.1.

Similar proteinsi

Entry informationi

Entry nameiU3CMY2_CALJA
AccessioniPrimary (citable) accession number: U3CMY2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: October 25, 2017
This is version 34 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)