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Protein
Submitted name:

Alpha-amylase

Gene

LY180_10000

Organism
Escherichia coli LY180
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei235 – 2351NucleophileUniRule annotation
Active sitei265 – 2651Proton donorUniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylaseImported (EC:3.2.1.1Imported)
Gene namesi
ORF Names:LY180_10000Imported
OrganismiEscherichia coli LY180Imported
Taxonomic identifieri1335916 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000016700: Chromosome

Structurei

3D structure databases

ProteinModelPortaliT2FZ30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

KOiK01176.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

T2FZ30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNPTLLQCF HWYYPEGGKL WPELAERADG FNDIGINMVW LPPAYKGASG
60 70 80 90 100
GYSVGYDSYD LFDLGEFDQK GSIPTKYGDK AQLLAAIDAL KRNDIAVLLD
110 120 130 140 150
VVVNHKMGAD EKEAIRVQRV NADDRTQIDE EIIECEGWTR YTFPARAGQY
160 170 180 190 200
SQFIWDFKCF SGIDHIENPD EDGIFKIVND YTGEGWNDQV DDELGNFDYL
210 220 230 240 250
MGENIDFRNH AVTEEIKYWA RWVMEQTQCD GFRLDAVKHI PAWFYKEWIE
260 270 280 290 300
HVQEVAPKPL FIVAEYWSHE VDKLQTYIDQ VEGKTMLFDA PLQMKFHEAS
310 320 330 340 350
RMGRDYDMTQ IFTGTLVEAD PFHAVTLVAN HDTQPLQALE APVEPWFKPL
360 370 380 390 400
AYALILLREN GVPSVFYPDL YGAHYEDVGG DGQTYPIDMP IIEQLDELIL
410 420 430 440 450
ARQRFAHGVQ TLFFDHPNCI AFSRSGTDEY PGCVVVMSNG DDGEKTINLG
460 470 480 490
ENYGNKTWRD FLGNRQESVV TDENGEATFF CNGGSVSVWV IEEVI
Length:495
Mass (Da):56,563
Last modified:November 13, 2013 - v1
Checksum:iA0661DC87F49C4D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006584 Genomic DNA. Translation: AGW09176.1.
RefSeqiYP_008565099.1. NC_022364.1.

Genome annotation databases

EnsemblBacteriaiAGW09176; AGW09176; LY180_10000.
GeneIDi16979671.
KEGGiecol:LY180_10000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP006584 Genomic DNA. Translation: AGW09176.1.
RefSeqiYP_008565099.1. NC_022364.1.

3D structure databases

ProteinModelPortaliT2FZ30.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAGW09176; AGW09176; LY180_10000.
GeneIDi16979671.
KEGGiecol:LY180_10000.

Phylogenomic databases

KOiK01176.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Polyamine Transporters and Polyamines Increase Furfural Tolerance during Xylose Fermentation with Ethanologenic Escherichia coli Strain LY180."
    Geddes R.D., Wang X., Yomano L.P., Miller E.N., Zheng H., Shanmugam K.T., Ingram L.O.
    Appl. Environ. Microbiol. 80:5955-5964(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LY180Imported.

Entry informationi

Entry nameiT2FZ30_ECOLX
AccessioniPrimary (citable) accession number: T2FZ30
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: February 4, 2015
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.