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T1R3D3

- T1R3D3_HUMAN

UniProt

T1R3D3 - T1R3D3_HUMAN

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Protein
Submitted name:

MHC class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. peptide antigen binding Source: InterPro

GO - Biological processi

  1. antigen processing and presentation of peptide antigen via MHC class I Source: InterPro
  2. immune response Source: InterPro
  3. positive regulation of T cell mediated cytotoxicity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class I antigenImported
Gene namesi
Name:HLA-CImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. MHC class I protein complex Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliT1R3D3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation

Family and domain databases

Gene3Di3.30.500.10. 1 hit.
InterProiIPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SUPFAMiSSF54452. SSF54452. 1 hit.

Sequencei

Sequence statusi: Fragment.

T1R3D3-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
SHSMRYFSTS VSWPGRGEPR FIAVGYVDDT QFVRFDSDAA SPRGEPREPW
60 70 80 90 100
VEQEGPEYWD RETQKYKRQA QADRVNLRKL RGYYNQSEDG SHTLQRMFGC
110 120 130 140 150
DLGPDGRLLR GYNQFAYDGK DYIALNEDLR SWTAADTAAQ ITQRKWEAAR
160 170 180
EAEQRRAYLE GTCVEWLRRY LENGKETLQR A
Length:181
Mass (Da):21,219
Last modified:November 13, 2013 - v1
Checksum:i93D08DECD4BBDD18
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei181 – 1811Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX842737 Genomic DNA. Translation: AGG79773.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JX842737 Genomic DNA. Translation: AGG79773.1 .

3D structure databases

ProteinModelPortali T1R3D3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-C. human.

Family and domain databases

Gene3Di 3.30.500.10. 1 hit.
InterProi IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view ]
Pfami PF00129. MHC_I. 1 hit.
[Graphical view ]
PRINTSi PR01638. MHCCLASSI.
SUPFAMi SSF54452. SSF54452. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "HLA new alleles found by Histogenetics."
    Cereb N., Yang S.Y.
    Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiT1R3D3_HUMAN
AccessioniPrimary (citable) accession number: T1R3D3
Entry historyi
Integrated into UniProtKB/TrEMBL: November 13, 2013
Last sequence update: November 13, 2013
Last modified: November 26, 2014
This is version 6 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.