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Protein
Submitted name:

Frizzled-7 isoform 1

Gene

CB1_001286005

Organism
Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinSAAS annotation, ReceptorSAAS annotation
Biological processWnt signaling pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Frizzled-7 isoform 1Imported
Gene namesi
ORF Names:CB1_001286005Imported
OrganismiCamelus ferus (Wild bactrian camel) (Camelus bactrianus ferus)Imported
Taxonomic identifieri419612 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaTylopodaCamelidaeCamelus
Proteomesi
  • UP000030684 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei383 – 405HelicalSequence analysisAdd BLAST23
Transmembranei417 – 437HelicalSequence analysisAdd BLAST21
Transmembranei466 – 492HelicalSequence analysisAdd BLAST27
Transmembranei557 – 578HelicalSequence analysisAdd BLAST22
Transmembranei599 – 620HelicalSequence analysisAdd BLAST22
Transmembranei655 – 677HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi191 ↔ 252PROSITE-ProRule annotation
Disulfide bondi199 ↔ 245PROSITE-ProRule annotation
Disulfide bondi266 ↔ 290PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini186 – 305FZInterPro annotationAdd BLAST120
Domaini381 – 684G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST304

Sequence similaritiesi

Belongs to the G-protein coupled receptor Fz/Smo family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiView protein in InterPro
IPR015526. Frizzled/SFRP.
IPR000539. Frizzled/Smoothened_TM.
IPR020067. Frizzled_dom.
IPR036790. Frizzled_dom_sf.
IPR026552. FZD7.
IPR017981. GPCR_2-like.
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF31. PTHR11309:SF31. 1 hit.
PfamiView protein in Pfam
PF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
PRINTSiPR00489. FRIZZLED.
SMARTiView protein in SMART
SM00063. FRI. 1 hit.
SM01330. Frizzled. 1 hit.
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiView protein in PROSITE
PS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Complete.

S9WNB8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALPSHCHRA VENTLHSPAA ACQRQTADRS GNGTQIPPSQ PPFDVCGTEH
60 70 80 90 100
VKRYGLKRVT KSKKRQQFYL INDFKASETY PSGIQLWGWY CDALVLDRGA
110 120 130 140 150
HPDRGPPWDP RQLGKEPAKG PWKVNRAGPI TSYGNVCVTG KRIIQGCAAA
160 170 180 190 200
SRSPLGLCTL VLALLGALPA GARAQPYHGE KGISVPDHGF CQPISIPLCT
210 220 230 240 250
DIAYNQTILP NLLGHTNQED AGLEVHQFYP LVKVQCSPEL RFFLCSMYAP
260 270 280 290 300
VCTVLDKAIP PCRSLCERAR QGCEALMNKF GFQWPERLRC ENFPVHGAGE
310 320 330 340 350
ICVGQNTSDG SGGPGGGPTA YPTAPYMPDL PFTAPSPPCP RLKVPPYLGY
360 370 380 390 400
RFLGERDCGA PCEPGRANGL MYFKEEERRF ARLWVGVWSV LCCASTLFTV
410 420 430 440 450
LTYLVDMRRF SYPERPIIFL SGCYFMVAVA HVAGFLLEDR AVCVERFSDD
460 470 480 490 500
GYRTVAQGTK KEGCTILFMV LYFFGMASSI WWVILSLTWF LAAGMKWGHE
510 520 530 540 550
AIEANSQYFH LAAWAVPAVK TITILAMGQV DGDLLSGVCY VGLSSVDALR
560 570 580 590 600
GFVLAPLFVY LFIGTSFLLA GFVSLFRIRT IMKHDGTKTE KLEKLMVRIG
610 620 630 640 650
VFSVLYTVPA TIVLACYFYE QAFREHWERT WLLQTCKSYA VPCPPGHFPP
660 670 680 690 700
MSPDFTVFMI KYLMTMIVGI TTGFWIWSGK TLQSWRRFYH RLSHSSKGET

AV
Length:702
Mass (Da):78,110
Last modified:October 16, 2013 - v1
Checksum:i38B4157249E7BB0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB017491 Genomic DNA. Translation: EPY77234.1.

Similar proteinsi

Entry informationi

Entry nameiS9WNB8_CAMFR
AccessioniPrimary (citable) accession number: S9WNB8
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: October 25, 2017
This is version 21 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported