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Protein

Purine nucleoside phosphorylase

Gene

CB1_001481042

Organism
Camelus ferus (Wild bactrian camel) (Camelus bactrianus ferus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.UniRule annotation

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation

Pathwayi: purine nucleoside salvage

This protein is involved in the pathway purine nucleoside salvage, which is part of Purine metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway purine nucleoside salvage and in Purine metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33PhosphateUniRule annotation1
Binding sitei64PhosphateUniRule annotation1
Binding sitei116Phosphate; via amide nitrogenUniRule annotation1
Binding sitei201Purine nucleosideUniRule annotation1
Binding sitei220PhosphateUniRule annotation1
Binding sitei243Purine nucleosideUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

UniPathwayiUPA00606.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylaseUniRule annotation (EC:2.4.2.1UniRule annotation)
Alternative name(s):
Inosine-guanosine phosphorylaseUniRule annotation
Gene namesi
ORF Names:CB1_001481042Imported
OrganismiCamelus ferus (Wild bactrian camel) (Camelus bactrianus ferus)Imported
Taxonomic identifieri419612 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaTylopodaCamelidaeCamelus
Proteomesi
  • UP000030684 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 276PNP_UDP_1InterPro annotationAdd BLAST250

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni84 – 86Phosphate bindingUniRule annotation3

Sequence similaritiesi

Belongs to the PNP/MTAP phosphorylase family.UniRule annotation

Phylogenomic databases

KOiK03783.

Family and domain databases

InterProiView protein in InterPro
IPR000845. Nucleoside_phosphorylase_d.
IPR035994. Nucleoside_phosphorylase_sf.
IPR011270. Pur_Nuc_Pase_Ino/Guo-sp.
IPR011268. Purine_phosphorylase.
IPR018099. Purine_phosphorylase-2_CS.
PANTHERiPTHR11904. PTHR11904. 1 hit.
PfamiView protein in Pfam
PF01048. PNP_UDP_1. 1 hit.
PIRSFiPIRSF000477. PurNPase. 1 hit.
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR01700. PNPH. 1 hit.
TIGR01697. PNPH-PUNA-XAPA. 1 hit.
PROSITEiView protein in PROSITE
PS01240. PNP_MTAP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

S9WKC6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIGFTYEDY QTTAKWLLSH TKHRPQVAVI CGSGLGGLTD RLTQTQIFDY
60 70 80 90 100
KEIPNFPRST VPGHAGRLVF GFLNGRACVM MQGRFHLYEG YPLWKVTFPV
110 120 130 140 150
RVFQLLGVDT LMVTNAAGGL NPKFEVGDIM LIRDHINLPG LCGENPLRGP
160 170 180 190 200
NEERFGVRFP AMSDAYDRDM RRKAHSTWKQ MGEQRELQEG TYVMVAGPSF
210 220 230 240 250
ETVAECRLLQ KLGADAVGMS TVPEVIVARH CGLRVFGFSL ITNKAILDYE
260 270 280
NQEKANHEEV LEAGKQAAQK LEQFVSILVA SIPLPGKAS
Length:289
Mass (Da):32,204
Last modified:October 16, 2013 - v1
Checksum:i5A062098EE14B426
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KB017655 Genomic DNA. Translation: EPY76199.1.
RefSeqiXP_006191289.1. XM_006191227.2.

Genome annotation databases

GeneIDi102521445.
KEGGicfr:102521445.

Similar proteinsi

Entry informationi

Entry nameiS9WKC6_CAMFR
AccessioniPrimary (citable) accession number: S9WKC6
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: October 25, 2017
This is version 20 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported