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Protein

5-formyltetrahydrofolate cyclo-ligase

Gene

SPOG_02977

Organism
Schizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691) (Fission yeast)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei52Substrate; via carbonyl oxygenUniRule annotation1
Binding sitei58SubstrateUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi6 – 10ATPUniRule annotation5
Nucleotide bindingi137 – 145ATPUniRule annotation9

GO - Molecular functioni

Keywordsi

Molecular functionLigaseImported
LigandATP-bindingUniRule annotation, MagnesiumUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
5-formyltetrahydrofolate cyclo-ligaseUniRule annotation (EC:6.3.3.2UniRule annotation)
Gene namesi
ORF Names:SPOG_02977Imported
OrganismiSchizosaccharomyces cryophilus (strain OY26 / ATCC MYA-4695 / CBS 11777 / NBRC 106824 / NRRL Y48691) (Fission yeast)Imported
Taxonomic identifieri653667 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000015464 Componenti: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.UniRule annotation

Phylogenomic databases

OrthoDBiEOG092C4TVL

Family and domain databases

Gene3Di3.40.50.10420, 1 hit
InterProiView protein in InterPro
IPR002698 FTHF_cligase
IPR024185 FTHF_cligase-like_sf
IPR037171 NagB/RpiA_transferase-like
PANTHERiPTHR23407:SF1 PTHR23407:SF1, 1 hit
PfamiView protein in Pfam
PF01812 5-FTHF_cyc-lig, 1 hit
PIRSFiPIRSF006806 FTHF_cligase, 1 hit
SUPFAMiSSF100950 SSF100950, 1 hit
TIGRFAMsiTIGR02727 MTHFS_bact, 1 hit

Sequencei

Sequence statusi: Complete.

S9W7B1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNFSKKKIR SLMSKVLAGL SDQLVEAEST SVCEKVLNLP EWKKSKNICL
60 70 80 90 100
FMNMPKMEIR THDLVNEALK QGKNVFLPRC EGRHTMSMYQ VYNTNHLIKN
110 120 130 140 150
QWQIPEPDGS SPKVMDDETF CDLIIMPGVA FDSNLARLGH GRGFYDDFVH
160 170 180 190 200
RYKAWCFQKP SRCDIFKVGI CLSKQVLPNG QIPMSPLDEF LDLLVTPQNI

YKRP
Length:204
Mass (Da):23,474
Last modified:October 16, 2013 - v1
Checksum:iFA32F36E4D638B69
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KE546988 Genomic DNA Translation: EPY53790.1
RefSeqiXP_013021092.1, XM_013165638.1

Genome annotation databases

EnsemblFungiiEPY53790; EPY53790; SPOG_02977
GeneIDi25037298

Similar proteinsi

Entry informationi

Entry nameiS9W7B1_SCHCR
AccessioniPrimary (citable) accession number: S9W7B1
Entry historyiIntegrated into UniProtKB/TrEMBL: October 16, 2013
Last sequence update: October 16, 2013
Last modified: April 25, 2018
This is version 22 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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